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• W2088543152 abstract "Five patients with Pneumocystis carinii pneumonia after heart transplantation are reported. Four had severe clinical symptoms, whereas 1 was asymptomatic. Mechanical ventilatory support was necessary in 1 because of respiratory distress. Pneumocystis carinii infection developed in 4 patients within the first 4 postoperative months, and 1 patient had clinical disease 1 year after transplantation with a recurrence 9 months later. All were treated with trimethoprim-sulfamethoxazole either orally or intravenously (10 to 20 mg.kg-1.day-1 of trimethoprim). All patients recovered from infection and received the same drug prophylactically for 2 to 20 months after the infection. All patients are doing well after Pneumocystis carinii infection except 1 who died after an acute myocardial infarction 4 years after infection. We conclude that trimethoprim-sulfamethoxazole is an effective agent for the treatment of Pneumocystis carinii pneumonia after heart transplantation." @default.
• W2088543152 created "2016-06-24" @default.
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• W2088543152 date "1991-07-01" @default.
• W2088543152 modified "2023-09-26" @default.
• W2088543152 title "Pneumocystis carinii pneumonia after heart transplantation" @default.
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• W2088543152 doi "https://doi.org/10.1016/0003-4975(91)91429-y" @default.
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