Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088562134> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2088562134 endingPage "154" @default.
- W2088562134 startingPage "149" @default.
- W2088562134 abstract "The Saccharomyces cerevisiae gene, ADE6, encoding 5'-phosphoribosylformyl glycinamidine synthetase (EC 6.3.5.3) has been cloned by complementation of an ade6 auxotroph. Transformation of ade6 mutants with ADE6-carrying centromeric plasmids restored normal, adenine-independent growth behavior in the recipients. Strains containing a disrupted ade6 allele were constructed and behaved as stable adenine auxotrophs. Southern transfer and genetic analyses of strains carrying a disrupted ade6 allele demonstrated that the cloned gene was ADE6 and not a suppressor. The cloned ADE6 DNA was mapped on the RAD2-proximal fragment of chromosome VII by hybridization on yeast chromosomes separated by pulsed-field gel electrophoresis. Northern-blot hybridization experiments show that the ADE6 region produces two different mRNA species of approx. 5 and 2 kb. Disappearance of the larger, but not the smaller, transcript is associated with ade6 mutations. A threefold repression in the amount of the 5-kb ADE6 mRNA is observed when growth medium is supplemented with exogenous adenine." @default.
- W2088562134 created "2016-06-24" @default.
- W2088562134 creator A5026820819 @default.
- W2088562134 creator A5058082421 @default.
- W2088562134 creator A5086577855 @default.
- W2088562134 date "1991-10-01" @default.
- W2088562134 modified "2023-09-24" @default.
- W2088562134 title "Cloning and transcriptional analysis of the ADE6 gene of Saccharomyces cerevisiae" @default.
- W2088562134 cites W1488068148 @default.
- W2088562134 cites W1519366937 @default.
- W2088562134 cites W1537782690 @default.
- W2088562134 cites W1591599155 @default.
- W2088562134 cites W1659736313 @default.
- W2088562134 cites W167820155 @default.
- W2088562134 cites W1973782344 @default.
- W2088562134 cites W2017352502 @default.
- W2088562134 cites W2029987769 @default.
- W2088562134 cites W2050060181 @default.
- W2088562134 cites W2068480850 @default.
- W2088562134 cites W2081564264 @default.
- W2088562134 cites W2087777628 @default.
- W2088562134 cites W2162382740 @default.
- W2088562134 cites W2171885622 @default.
- W2088562134 cites W4250090422 @default.
- W2088562134 cites W91844216 @default.
- W2088562134 doi "https://doi.org/10.1016/0378-1119(91)90309-y" @default.
- W2088562134 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1743513" @default.
- W2088562134 hasPublicationYear "1991" @default.
- W2088562134 type Work @default.
- W2088562134 sameAs 2088562134 @default.
- W2088562134 citedByCount "17" @default.
- W2088562134 countsByYear W20885621342012 @default.
- W2088562134 crossrefType "journal-article" @default.
- W2088562134 hasAuthorship W2088562134A5026820819 @default.
- W2088562134 hasAuthorship W2088562134A5058082421 @default.
- W2088562134 hasAuthorship W2088562134A5086577855 @default.
- W2088562134 hasConcept C104317684 @default.
- W2088562134 hasConcept C121050878 @default.
- W2088562134 hasConcept C133307689 @default.
- W2088562134 hasConcept C143065580 @default.
- W2088562134 hasConcept C150194340 @default.
- W2088562134 hasConcept C153911025 @default.
- W2088562134 hasConcept C188082640 @default.
- W2088562134 hasConcept C19924922 @default.
- W2088562134 hasConcept C199360897 @default.
- W2088562134 hasConcept C204241405 @default.
- W2088562134 hasConcept C20950039 @default.
- W2088562134 hasConcept C22744801 @default.
- W2088562134 hasConcept C2777576037 @default.
- W2088562134 hasConcept C41008148 @default.
- W2088562134 hasConcept C54355233 @default.
- W2088562134 hasConcept C86803240 @default.
- W2088562134 hasConceptScore W2088562134C104317684 @default.
- W2088562134 hasConceptScore W2088562134C121050878 @default.
- W2088562134 hasConceptScore W2088562134C133307689 @default.
- W2088562134 hasConceptScore W2088562134C143065580 @default.
- W2088562134 hasConceptScore W2088562134C150194340 @default.
- W2088562134 hasConceptScore W2088562134C153911025 @default.
- W2088562134 hasConceptScore W2088562134C188082640 @default.
- W2088562134 hasConceptScore W2088562134C19924922 @default.
- W2088562134 hasConceptScore W2088562134C199360897 @default.
- W2088562134 hasConceptScore W2088562134C204241405 @default.
- W2088562134 hasConceptScore W2088562134C20950039 @default.
- W2088562134 hasConceptScore W2088562134C22744801 @default.
- W2088562134 hasConceptScore W2088562134C2777576037 @default.
- W2088562134 hasConceptScore W2088562134C41008148 @default.
- W2088562134 hasConceptScore W2088562134C54355233 @default.
- W2088562134 hasConceptScore W2088562134C86803240 @default.
- W2088562134 hasIssue "1" @default.
- W2088562134 hasLocation W20885621341 @default.
- W2088562134 hasLocation W20885621342 @default.
- W2088562134 hasOpenAccess W2088562134 @default.
- W2088562134 hasPrimaryLocation W20885621341 @default.
- W2088562134 hasRelatedWork W1776753901 @default.
- W2088562134 hasRelatedWork W1965684540 @default.
- W2088562134 hasRelatedWork W1977744274 @default.
- W2088562134 hasRelatedWork W2024072476 @default.
- W2088562134 hasRelatedWork W2049520323 @default.
- W2088562134 hasRelatedWork W2074572604 @default.
- W2088562134 hasRelatedWork W2088562134 @default.
- W2088562134 hasRelatedWork W2094132976 @default.
- W2088562134 hasRelatedWork W2114217399 @default.
- W2088562134 hasRelatedWork W2302204669 @default.
- W2088562134 hasVolume "107" @default.
- W2088562134 isParatext "false" @default.
- W2088562134 isRetracted "false" @default.
- W2088562134 magId "2088562134" @default.
- W2088562134 workType "article" @default.