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• W2088575676 abstract "British Journal of HaematologyVolume 40, Issue 4 p. 509-517 THE DIFFERENTIATION OF MYELOID LEUKAEMIA CELLS: NEW POSSIBILITIES FOR THERAPY L. Sachs, Corresponding Author L. Sachs Department of Genetics, Weizmann Institute of Science, Reho vot, IsraelProfessor Leo Sachs, Department of Genetics, Weizmann Institute of Science, Rehovot, Israel.Search for more papers by this author L. Sachs, Corresponding Author L. Sachs Department of Genetics, Weizmann Institute of Science, Reho vot, IsraelProfessor Leo Sachs, Department of Genetics, Weizmann Institute of Science, Rehovot, Israel.Search for more papers by this author First published: December 1978 https://doi.org/10.1111/j.1365-2141.1978.tb05826.xCitations: 138AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL REFERENCES Austin, P.E., McCulloch, E.A. & Till, J.E. (1971) Characterization of the factor in L-cell conditioned medium capable of stimulating colony formation by mouse marrow cells in culture. Journal of Cellular Physiology, 77, 121– 134. Azumi, J. & Sachs, L. (1977) Chromosome mapping of the genes that control differentiation and malignancy in myeloid leukemic cells. Proceedings of the National Academy of Sciences of the United States of America, 74, 257– 257. Barak, Y., Paran, M., Levin, S. & Sachs, L. (1971) In vitro induction of myeloid proliferation and maturation in infantile genetic agranulocytosis. Blood, 38, 74– 80. Bradely, T.R. & Metcalf, D. (1966) The growth of mouse bone marrow cells in vitro. Australian Journal of Experimental Biology and Medical Sciences, 44, 287– 300. Burgess, A.W., Camakaris, J. & Metcalf, D. (1977) Purification and properties of colony-stimulating factor from mouse lung-conditioned medium. Journal of Biological Chemistry, 252, 1998– 2003. Dexter, T.M., Allen, T.D. & Lajtha, L.G. (1977) Conditions controlling the proliferation of haemopoietic stem cells in vitro. Journal of Cellular Physiology, 91, 335– 344. Fibach, E., Gerassi, E. & Sachs, L. (1976) Induction of colony formation in vitro, by human lymphocytes. Nature, 259, 127– 129. Fibach, E., Hayashi, M. & Sachs, L. (1973) Control of normal differentiation of myeloid leukemic cells to macrophages and granulocytes. Proceedings of the National Academy of Sciences of the United States of America, 70, 343– 346. Fibach, E., Landau, T. & Sachs, L. (1972) Normal differentiation of myeloid leukaemic cells induced by a differentiation-inducucing protein. Nature: New Biology, 237, 276– 278. Fibach, E., & Sachs, L. (1975) Control of normal differentiation of myeloid leukemic cells. VIII. Induction of differentiation to mature granulocytes in mass culture. Journal of Cellular Physiology, 86, 221– 230. Fibach, E. & Sachs, L. (1976) Control of normal differentiation of myeloid leukemic cells. XI. Induction of a specific requirement for cell viability and growth during the differentiation of myeloid leukemic cells. Journal of Cellular Physiology, 89, 259– 266. Friend, C., Scher, W., Holland, J.G. & Sato, T. (1971) Hemoglobin synthesis in murine virus-infected leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide. Proceedings of the National Academy of Sciences of the United States of America, 68, 378– 382. Gerassi, E. & Sachs, L. (1976) Regulation of the induction of colonies in vitro, by normal human lymphocytes. Proceedings of the National Academy of Sciences of the United States of America, 73, 4546– 4550. Ginsburg, H. & Sachs, L. (1963) Formation of pure suspensions of mast cells in tissue culture by differentiation of lymphoid cells from the mouse thymus. Journal of the National Cancer Institute, 31, 1– 40. Ginsburg, H. & Sachs, L. (1965) Destruction of mouse and rat embryo cells in tissue culture by lymph node cells from unsensitized rats. Journal of Cellular and Comparative Physiology, 66, 199– 220. Guez, M. & Sachs, L. (1973) Purification of the protein that induces cell differentiation to macrophages and granulocytes. FEBS Letters, 37, 149– 154. Ichikawa, Y. (1969) Differentiation of a cell line of myeloid leukemia. Journal of Cellular Physiology, 74, 223– 234. Ichikawa, Y., Pluznik, D.H. & Sachs, L. (1966) In vitro control of the development of macrophage and granulocyte colonies. Proceedings of the National Academy of Sciences of the United States of America, 56, 488– 495. Ichikawa, Y., Pluznik, D.H. & Sachs, L. (1967) Feedback inhibition of the development of macrophage and granulocyte colonies. I. Inhibition by macrophages. Proceedings of the National Academy of Sciences of the United States of America, 58, 1480– 1486. Krantz, S.B. & Jacobson, L.O. (1970) Erythropoietin and the Regulation of Erythropoiesis. University of Chicago Press. Kluge, N., Gaedicke, G., Steinheider, G., Dube, S. & Ostertag, W. (1974) Globin synthesis in Friend-erythroleukemia mouse cells in protein- and lipid-free medium. Experimental Cell Research, 88, 257– 262. Krystosek, A. & Sachs, L. (1976) Control of lysozyme induction in the differentiation of myeloid leukemic cells. Cell, 9, 675– 684. Krystosek, A. & Sachs, L. (1977) Steroid hormone receptors and the differentiation of myeloid leukemic cells. Journal of Cellular Physiology, 92, 345– 352. Landau, T. & Sachs, L. (1971) Characterization of the inducer required for the development of macrophage and granulocyte colonies. Proceedings of the National Academy of Sciences of the United States of America, 68, 2540– 2544. Liebermann, D. & Sachs, L. (1977) Type C RNA virus production and cell competence for normal differentiation in myeloid leukemic cells. Nature, 269, 173– 175. Lotem, J. & Sachs, L. (1974) Different blocks in the differentiation of myeloid leukemic cells. Proceedings of the National Academy of Sciences of the United States of America, 71, 3507– 3511. Lotem, J. & Sachs, L. (1975a) Induction of specific changes in the surface membrane of myeloid leukemic cells by steroid hormones. International Journal of Cancer, 15, 731– 740. Lotem, J. & Sachs, L. (1975b) Control of normal differentiation of myeloid leukemic cells. VI. Inhibition of cell multiplication and the formation of macrophages. Journal of Cellular Physiology, 85, 587– 594. Lotem, J. & Sachs, L. (1976) Control of Fc and C3 receptors on myeloid leukemic cells. Journal of Immunology, 117, 580– 586. Lotem, J. & Sachs, L. (1977a) Control of normal differentiation of myeloid leukemic cells. XII. Isolation of normal myeloid colony-forming cells from bone marrow and the sequence of differentiation to mature granulocytes in normal and D+ myeloid leukemic cells. Journal of Cellular Physiology, 92, 97– 108. Lotem, J. & Sachs, L. (1977b) Genetic dissection of the control of normal differentiation in myeloid leukemic cells. Proceedings of the National Academy of Sciences of the United States of America, 74, 5554– 5558. Lotem, J. & Sachs, L. (1978) In vivo induction of normal differentiation in myeloid leukemic cells. Proceedings of the National Academy of Sciences of the United States of America, (in press). Lotem, J., Vlodavsky, I. & Sachs, L. (1976) Regulation of cap formation by concanavalin A and the differentiation of myeloid leukemic cells: Relationship to free and anchored surface receptors. Experimental Cell Research, 101, 323– 330. Maeda, S. & Sachs, L. (1978) Control of normal differentiation of myeloid leukemic cells. XIII. Inducibility for some stages of differentiation by dimethylsulfoxide and its dissociation from inducibility by MGI. Journal of Cellular Physiology, 94, 181– 186. Metcalf, D. (1969) Studies on colony formation in vitro by mouse bone marrow cells. I. Continuous cluster formation and relation of clusters to colonies. Journal of Cellular Physiology, 74, 323– 332. Metcalf, D., Nossal, G.J.V., Warner, N.L., Miller, J.F.A.P., Mandel, T.E. Layton, J.E. & Gutman, G.A. (1975) Growth of B-lymphocyte colonies in vitro. Journal of Experimental Medicine, 142, 1534– 1549. Mintz, B. & Illmensee, K. (1975) Normal genetically mosaic mice produced from malignant teratocarcinoma cells. Proceeding of the National Academy of Sciences of the United States of America, 72, 3585– 3589. Mintz, U. & Sachs, L. (1973a) Normal granulocyte colony-forming cells in the bone marrow of Yemenite Jews with genetic neutroperia. Blood, 41, 745– 751. Mintz, U. & Sachs, L. (1973b) Differnces in inducing activity for human bone marrow colonies in normal serum and serum from patients with leukemia. Blood, 42, 331– 339. Nudel, U., Salmon, J.E., Terada, M., Bank, A., Rifkind, R.A. & Marks, P.A. (1977) Differential effects of chemical inducers on expression of β globin genes in murine erythroleukemia cells. Proceedings of the National Academy of Sciences of the United States of America, 74, 1100– 1104. Ohta, Y., Tanaka, M., Terada, M., Miller, O.J., Bank, A., Marks, P.A. & Rifkind, R.A. (1976) Erythroid cell differentiation: Murine erythroleukemia cell variant with unique pattern of induction by polar compounds. Proceedings of the National Academy of Sciences of the United States of America, 73, 1232– 1236. Paran, M. & Sachs, L. (1968) The continued requirement for inducer for the development of macrophage and granulocyte colonies. Journal of Cellular Physiology, 72, 247– 250. Paran, M., Sachs, L., Barak, Y. & Resnitzky, P. (1970) In vitro induction of granulocyte differentiation in hematopoietic cells from leukemic and nonleukemic patients. Proceedings of the National Academy of Sciences of the United States of America, 67, 1542– 1549. Pluznik, D.H. & Sachs, L. (1965) The cloning of normal “mast” cell in tissue culture. Journal of Cellular and Comarative Physiology, 66, 319– 324. Pluznik, D.H. & Sachs, L. (1966) The induction of clones of normal “mast” cells by a substance from conditioned medium. Experimental Cell Research, 43, 553– 563. Rowley, J.D. (1977) Mapping of human chromosomal regions related to neoplasia: Evidence form chromosomes 1 and 17. Proceedings of the National Academy of Sciences of the United States of America, 74, 5729– 5733. Sachs, L. (1964) The analysis of regulatory mechanisms in cell differentiation. New Perspectives in Biology, pp. 246– 260. Elsevier, Amsterdam . Sachs, L. (1974a) Regulation of membrane changes, differentiation and malignancy in carcinogenesis. Harvey Lectures, 68, 1– 35. Academic Press, New York . Sachs, L. (1974b) Control of growth and differentiation in normal hematopoietic and leukemic cells. Control of Proliferation in Animal Cells, pp. 915– 925. Cold Spring Harbor Lab., New York . Sachs, L. (1976) Control of normal cell differentiation in leukemic cells. Comparative Leukemia Research, pp. 6– 9. Karger, Basel . Sachs, L. (1978) Control of normal cell differentiation in leukemic white blood cells. In: M.D. Anderson Symposium on Cell Differentiation and Neoplasia, pp. 223– 239. Raven Press, New York . Simantov, R. & Sachs, L. (1978) Differential desensitization of functiona adrenergic receptors in normal and malignancy myeloid cells. Relationship to receptor mediated hormone cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America, 75, 1805– 1809. Sredni, B., Kalechman, Y., Michlin, H. & Rozenszajn, L.A. (1976) Development of colonies in vitro of mitogen-stimulated mouse T lymphocytes. Nature, 259, 130– 132. Stanley, E.R. & Heard, P.M. (1977) Factors regulating macrophage production and growth, purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells. Journal of Biological Chemistry, 252, 4305– 4312. Stephenson, J.R., Axelrad, A.A., McLeod, D.L. & Shreeve, M.M. (1971) Induction of colonies of hemoglobin-synthesizing cells by erythropoietin in vitro. Proceedings of the National Academy of Sciences of the United States of America, 68, 1542– 1546. Weiss, B. & Sachs, L. (1978) Indirect induction of differentiation in myeloid leukemic cells by lipid A. Proceedings of the National Academy of Sciences of the United States of America, 75, 1374– 1378. Citing Literature Volume40, Issue4December 1978Pages 509-517 ReferencesRelatedInformation" @default.
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