FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088598791> ?p ?o ?g. }

• W2088598791 endingPage "801" @default.
• W2088598791 startingPage "791" @default.
• W2088598791 abstract "Amphipathic α-helices play a crucial role in mediating the interaction of peptides and proteins with membranes. We have analyzed protein structures for the occurrence of 18-residue amphipathic helices. We find several of these α-helices having average hydrophobic moments and average hydrophobicities that would favor their interaction with membranes. We have analyzed the distribution of net charge, helix length, normalized frequency of occurrence, and propensities of the 20 amino acids in the delineated 18-residue helices. We have observed distinct differences in the frequencies of occurrence of polar and hydrophobic amino acids at positions 1–18 in amphipathic and nonamphipathic helices. There are also differences in propensities of the 20 amino acids to occur at positions 1–18 of amphipathic and nonamphipathic helices. Synthetic peptides corresponding to some of these surface-seeking helices do possess antibacterial and/or hemolytic activities. Knowledge of the distribution of charges in 18-residue surface-seeking amphipathic α-helices, as well as propensity of occurrence of amino acids at various positions, would be useful inputs in the de novo design of amphipathic peptides. Proteins 2005. © 2005 Wiley-Liss, Inc." @default.
• W2088598791 created "2016-06-24" @default.
• W2088598791 creator A5020687804 @default.
• W2088598791 creator A5050403051 @default.
• W2088598791 creator A5066867605 @default.
• W2088598791 date "2005-04-08" @default.
• W2088598791 modified "2023-09-24" @default.
• W2088598791 title "Amphipathic α-helices in proteins: Results from analysis of protein structures" @default.
• W2088598791 cites W1495099700 @default.
• W2088598791 cites W1516030996 @default.
• W2088598791 cites W1546896179 @default.
• W2088598791 cites W1554728849 @default.
• W2088598791 cites W1569553189 @default.
• W2088598791 cites W1966552786 @default.
• W2088598791 cites W1971024387 @default.
• W2088598791 cites W1977842852 @default.
• W2088598791 cites W1979764309 @default.
• W2088598791 cites W1983521156 @default.
• W2088598791 cites W1986191025 @default.
• W2088598791 cites W1988048149 @default.
• W2088598791 cites W1990198570 @default.
• W2088598791 cites W1995936058 @default.
• W2088598791 cites W1999004357 @default.
• W2088598791 cites W2002066211 @default.
• W2088598791 cites W2007415752 @default.
• W2088598791 cites W2008922464 @default.
• W2088598791 cites W2009440109 @default.
• W2088598791 cites W2020790969 @default.
• W2088598791 cites W2023832016 @default.
• W2088598791 cites W2029743627 @default.
• W2088598791 cites W2033299688 @default.
• W2088598791 cites W2044897724 @default.
• W2088598791 cites W2051485189 @default.
• W2088598791 cites W2056502094 @default.
• W2088598791 cites W2056770911 @default.
• W2088598791 cites W2063737329 @default.
• W2088598791 cites W2068221306 @default.
• W2088598791 cites W2080686432 @default.
• W2088598791 cites W2081359387 @default.
• W2088598791 cites W2095967561 @default.
• W2088598791 cites W2100584305 @default.
• W2088598791 cites W2107876005 @default.
• W2088598791 cites W2113403117 @default.
• W2088598791 cites W2114471659 @default.
• W2088598791 cites W2123501118 @default.
• W2088598791 cites W2126469537 @default.
• W2088598791 cites W2127045036 @default.
• W2088598791 cites W2127960367 @default.
• W2088598791 cites W2135499146 @default.
• W2088598791 cites W2141920771 @default.
• W2088598791 cites W2165500804 @default.
• W2088598791 cites W2616374847 @default.
• W2088598791 cites W3047703793 @default.
• W2088598791 cites W4240607472 @default.
• W2088598791 doi "https://doi.org/10.1002/prot.20459" @default.
• W2088598791 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15822124" @default.
• W2088598791 hasPublicationYear "2005" @default.
• W2088598791 type Work @default.
• W2088598791 sameAs 2088598791 @default.
• W2088598791 citedByCount "17" @default.
• W2088598791 countsByYear W20885987912012 @default.
• W2088598791 countsByYear W20885987912013 @default.
• W2088598791 countsByYear W20885987912015 @default.
• W2088598791 countsByYear W20885987912016 @default.
• W2088598791 countsByYear W20885987912017 @default.
• W2088598791 countsByYear W20885987912018 @default.
• W2088598791 countsByYear W20885987912019 @default.
• W2088598791 countsByYear W20885987912020 @default.
• W2088598791 countsByYear W20885987912021 @default.
• W2088598791 countsByYear W20885987912022 @default.
• W2088598791 crossrefType "journal-article" @default.
• W2088598791 hasAuthorship W2088598791A5020687804 @default.
• W2088598791 hasAuthorship W2088598791A5050403051 @default.
• W2088598791 hasAuthorship W2088598791A5066867605 @default.
• W2088598791 hasConcept C12554922 @default.
• W2088598791 hasConcept C144647389 @default.
• W2088598791 hasConcept C15920480 @default.
• W2088598791 hasConcept C178790620 @default.
• W2088598791 hasConcept C184538305 @default.
• W2088598791 hasConcept C185592680 @default.
• W2088598791 hasConcept C18903297 @default.
• W2088598791 hasConcept C2778530040 @default.
• W2088598791 hasConcept C2779965526 @default.
• W2088598791 hasConcept C2781338088 @default.
• W2088598791 hasConcept C41625074 @default.
• W2088598791 hasConcept C47701112 @default.
• W2088598791 hasConcept C515207424 @default.
• W2088598791 hasConcept C521977710 @default.
• W2088598791 hasConcept C55493867 @default.
• W2088598791 hasConcept C67407626 @default.
• W2088598791 hasConcept C71240020 @default.
• W2088598791 hasConcept C8010536 @default.
• W2088598791 hasConcept C86803240 @default.
• W2088598791 hasConceptScore W2088598791C12554922 @default.
• W2088598791 hasConceptScore W2088598791C144647389 @default.
• W2088598791 hasConceptScore W2088598791C15920480 @default.
• W2088598791 hasConceptScore W2088598791C178790620 @default.
• W2088598791 hasConceptScore W2088598791C184538305 @default.

• next