FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088646178> ?p ?o ?g. }

• W2088646178 endingPage "504" @default.
• W2088646178 startingPage "496" @default.
• W2088646178 abstract "IN ORDER TO study the role of the Ca2+/calmodulin/myosin light chain kinase system in the development of chronic vasospasm caused by subarachnoid hemorrhage, the cytosolic Ca2+ level ([Ca2+]i), measured with fura-2, a fluorescent Ca2+ indicator, and contractile tension were measured simultaneously, and their quantitive correlation was examined in basilar arterial tissue obtained from the canine “two-hemorrhage” model. Sixteen adult mongrel dogs were divided into two groups, control (n = 8) and vasospasm (n = 8), and were killed 7 days after the first experimental subarachnoid hemorrhage. In basilar arterial tissue loaded with fura-2, 1) [Ca2+]i in the resting condition was not significantly different between the two groups; 2) the increment in [Ca2+]i induced by 40 mmol/L K+ stimulation was significantly smaller in vasospastic tissue (P < 0.01); and 3) 40 mmol/L K+-induced tension development per cross-sectional area for a fixed increment in [Ca2+]i was significantly greater in vasospastic tissue (P < 0.01). In tissue not loaded with fura-2, active myogenic tone, which was tentatively represented by the ratio of tonus relaxed with 10−4 mol/L papaverine to initial resting tone, was significantly greater in vasospastic tissue (P < 0.05). These findings, coupled with recent reports concerning the ratio of phosphorylated myosin light chain, indicate the following about vasospastic arterial tissue in vitro: 1) in the resting condition, augmented myogenic tone, which is not accompanied by [Ca2+]i elevation, is probably not attributable to the Ca2+/calmodulin/myosin light chain kinase system, and by contrast, 2) at a higher level of [Ca2+]i, a stronger contraction for a fixed increment in [Ca2+]i is induced by Ca2+ sensitization mechanisms of the calmodulin/myosin light chain kinase system." @default.
• W2088646178 created "2016-06-24" @default.
• W2088646178 creator A5018970044 @default.
• W2088646178 creator A5030339151 @default.
• W2088646178 creator A5038370468 @default.
• W2088646178 creator A5051645636 @default.
• W2088646178 creator A5071964268 @default.
• W2088646178 creator A5081592870 @default.
• W2088646178 date "1994-03-01" @default.
• W2088646178 modified "2023-10-15" @default.
• W2088646178 title "Relationship between Cytosolic Ca2+ Level and Contractile Tension in Canine Basilar Artery of Chronic Vasospasm" @default.
• W2088646178 cites W1964869616 @default.
• W2088646178 cites W1967016288 @default.
• W2088646178 cites W1972636782 @default.
• W2088646178 cites W1974592656 @default.
• W2088646178 cites W1998793671 @default.
• W2088646178 cites W1999132987 @default.
• W2088646178 cites W2006169703 @default.
• W2088646178 cites W2008334983 @default.
• W2088646178 cites W2025663530 @default.
• W2088646178 cites W2036375705 @default.
• W2088646178 cites W2046817990 @default.
• W2088646178 cites W2063008299 @default.
• W2088646178 cites W2068395560 @default.
• W2088646178 cites W2070819968 @default.
• W2088646178 cites W2080010271 @default.
• W2088646178 cites W2096257821 @default.
• W2088646178 cites W2107308340 @default.
• W2088646178 cites W2118005681 @default.
• W2088646178 cites W2124874778 @default.
• W2088646178 cites W2129132447 @default.
• W2088646178 cites W2141260882 @default.
• W2088646178 cites W2178203389 @default.
• W2088646178 cites W2439355660 @default.
• W2088646178 cites W2621332697 @default.
• W2088646178 cites W4213435391 @default.
• W2088646178 cites W4241640771 @default.
• W2088646178 doi "https://doi.org/10.1227/00006123-199403000-00016" @default.
• W2088646178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8190226" @default.
• W2088646178 hasPublicationYear "1994" @default.
• W2088646178 type Work @default.
• W2088646178 sameAs 2088646178 @default.
• W2088646178 citedByCount "19" @default.
• W2088646178 crossrefType "journal-article" @default.
• W2088646178 hasAuthorship W2088646178A5018970044 @default.
• W2088646178 hasAuthorship W2088646178A5030339151 @default.
• W2088646178 hasAuthorship W2088646178A5038370468 @default.
• W2088646178 hasAuthorship W2088646178A5051645636 @default.
• W2088646178 hasAuthorship W2088646178A5071964268 @default.
• W2088646178 hasAuthorship W2088646178A5081592870 @default.
• W2088646178 hasConcept C105702510 @default.
• W2088646178 hasConcept C12554922 @default.
• W2088646178 hasConcept C126322002 @default.
• W2088646178 hasConcept C134018914 @default.
• W2088646178 hasConcept C164705383 @default.
• W2088646178 hasConcept C181199279 @default.
• W2088646178 hasConcept C185592680 @default.
• W2088646178 hasConcept C2776952824 @default.
• W2088646178 hasConcept C2777736543 @default.
• W2088646178 hasConcept C2778470358 @default.
• W2088646178 hasConcept C2778506911 @default.
• W2088646178 hasConcept C2781012200 @default.
• W2088646178 hasConcept C29688787 @default.
• W2088646178 hasConcept C519063684 @default.
• W2088646178 hasConcept C55493867 @default.
• W2088646178 hasConcept C6997183 @default.
• W2088646178 hasConcept C71924100 @default.
• W2088646178 hasConcept C8035138 @default.
• W2088646178 hasConcept C86803240 @default.
• W2088646178 hasConcept C98539663 @default.
• W2088646178 hasConceptScore W2088646178C105702510 @default.
• W2088646178 hasConceptScore W2088646178C12554922 @default.
• W2088646178 hasConceptScore W2088646178C126322002 @default.
• W2088646178 hasConceptScore W2088646178C134018914 @default.
• W2088646178 hasConceptScore W2088646178C164705383 @default.
• W2088646178 hasConceptScore W2088646178C181199279 @default.
• W2088646178 hasConceptScore W2088646178C185592680 @default.
• W2088646178 hasConceptScore W2088646178C2776952824 @default.
• W2088646178 hasConceptScore W2088646178C2777736543 @default.
• W2088646178 hasConceptScore W2088646178C2778470358 @default.
• W2088646178 hasConceptScore W2088646178C2778506911 @default.
• W2088646178 hasConceptScore W2088646178C2781012200 @default.
• W2088646178 hasConceptScore W2088646178C29688787 @default.
• W2088646178 hasConceptScore W2088646178C519063684 @default.
• W2088646178 hasConceptScore W2088646178C55493867 @default.
• W2088646178 hasConceptScore W2088646178C6997183 @default.
• W2088646178 hasConceptScore W2088646178C71924100 @default.
• W2088646178 hasConceptScore W2088646178C8035138 @default.
• W2088646178 hasConceptScore W2088646178C86803240 @default.
• W2088646178 hasConceptScore W2088646178C98539663 @default.
• W2088646178 hasIssue "3" @default.
• W2088646178 hasLocation W20886461781 @default.
• W2088646178 hasLocation W20886461782 @default.
• W2088646178 hasOpenAccess W2088646178 @default.
• W2088646178 hasPrimaryLocation W20886461781 @default.
• W2088646178 hasRelatedWork W1974041169 @default.
• W2088646178 hasRelatedWork W1982932633 @default.
• W2088646178 hasRelatedWork W2014714141 @default.

• next