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- W2088670237 abstract "Combining Raman microscopy with a micro-capillary compartment enables spectroscopic studies of small amounts of biological material at variable pressure. We present experiments over the pressure range from atmospheric pressure to 4 kBar in a micro-capillary that use less than 100 nanoliters of sample. We investigate pressure dependent structural changes in DMPC and POPC lipid systems through measurements of the Raman spectrum in the CH2 stretch band and fingerprint regions. The micro-capillary also allows to enclose living cells and to optically interrogate them through a microscope. This is illustrated through Raman spectroscopy and direct optical imaging of individual red blood cells at variable pressure." @default.
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- W2088670237 date "2010-01-01" @default.
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- W2088670237 title "Micro-Spectroscopy of Biomolecules and Cells at Variable Pressure in a Micro-Capillary" @default.
- W2088670237 doi "https://doi.org/10.1016/j.bpj.2009.12.4068" @default.
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