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- W2088673062 abstract "Drs Morgan et al have to be congratulated for their excellent study on central retinal vein pulsations and vein pressure estimates in patients with glaucoma.1Morgan W.H. Hazelton M.L. Azar S.L. et al.Retinal venous pulsation in glaucoma and glaucoma suspects.Ophthalmology. 2004; 111: 1489-1494Abstract Full Text Full Text PDF PubMed Scopus (96) Google Scholar Their study is confirmed by another recent investigation using a similar ophthalmodynamometric device.2Jonas J.B. Central retinal artery and vein collapse pressure in eyes with chronic open angle glaucoma.Br J Ophthalmol. 2003; 87: 949-951Crossref PubMed Scopus (65) Google Scholar A previous histomorphometric investigation has suggested that the size of the aperture in the lamina cribrosa to allow passage to the central retinal artery and central retinal vein is independent of the size of the optic disc.3Jonas J.B. Mardin C.Y. Schlötzer-Schrehardt U. Naumann G.O. Morphometry of the human lamina cribrosa surface.Invest Ophthalmol Vis Sci. 1991; 32: 401-405PubMed Google Scholar This is consistent with the finding that the frequency of central retinal vein occlusions is independent of the optic disc size.4Strahlman E.R. Quinlan P.M. Enger C. Elman M.J. The cup-to-disc ratio and central retinal vein occlusion.Arch Ophthalmol. 1989; 107: 524-525Crossref PubMed Scopus (24) Google Scholar It may suggest that the venous trans-lamina cribrosa outflow resistance may be independent of the optic disc size. I ask the authors whether they have looked for such a relationship in their study. It may have clinical importance (i.e., for the discussion whether a radial optic neurotomy at the optic disc border in eyes with central retinal vein occlusion may decrease the venous trans-lamina cribrosa outflow resistance). Other histomorphometric studies have suggested that eyes with advanced glaucomatous optic nerve damage have a thinning and condensation of the lamina cribrosa that may explain an increased risk for further progression of glaucoma in patients with an advanced stage of the disease.5Jonas J.B. Berenshtein E. Holbach L. Anatomic relationship between lamina cribrosa, intraocular space, and cerebrospinal fluid space.Invest Ophthalmol Vis Sci. 2003; 44: 5189-5195Crossref PubMed Scopus (270) Google Scholar One may speculate that a glaucomatous deepening of the optic cup may be associated with a condensation of the lamina cribrosa, which may increase the venous trans-lamina cribrosa outflow resistance and influence the venous pulsations. I therefore ask the authors whether they have looked for a relationship between the depth of the optic cup and the ophthalmodynamometric measurements of the central retinal vein. Finally, the position of the central retinal vessel trunk in the lamina cribrosa and, indirectly, the shape of the optic disc may influence the segmental susceptibility for glaucomatous loss of the neuroretinal rim and enlargement of parapapillary atrophy.6Jonas J.B. Budde W.M. Németh J. et al.Central retinal vessel trunk exit and location of glaucomatous parapapillary atrophy in glaucoma.Ophthalmology. 2001; 108: 1059-1064Abstract Full Text Full Text PDF PubMed Scopus (51) Google Scholar I ask the authors whether they have information about an influence of the position of the central retinal vein in the lamina cribrosa and of the optic disc shape on the venous pulsations and ophthalmodynamometric estimations of the central retinal vein pressure." @default.
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- W2088673062 date "2005-05-01" @default.
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- W2088673062 title "Retinal Venous Pulsation and Glaucoma" @default.
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