FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088676196> ?p ?o ?g. }

• W2088676196 endingPage "546" @default.
• W2088676196 startingPage "529" @default.
• W2088676196 abstract "In this study, we evaluated the analgesic effect of the methanol extract of Kalanchoe gracilis (MKGS) stem in animal models by inducing writhing response with acetic acid and conducting formalin test. The anti-inflammatory effect of MKGS was also estimated on mice with λ-carrageenan induced paw edema model. In order to investigate the anti-inflammatory mechanism of MKGS, we analyzed the activities of glutathione peroxidase (GPx) and glutathione reductase (GRx) in the liver, and the levels of interleukin-1β (IL-1β), tumor necrosis factor (TNF-α), malondialdehyde (MDA) and nitric oxide (NO) in the edema paw tissue. In the analgesic tests, MKGS (0.5 and 1.0 g/kg) decreased both the acetic acid-induced writhing response and the licking time in the late phase of the formalin test. In the anti-inflammatory test, MKGS (0.1, 0.5 and 1.0 g/kg) decreased paw edema at the third, fourth, fifth and sixth hours after λ-carrageenan had been administrated. Furthermore, MKGS increased the activities of SOD and GRx in liver tissues and decreased MDA level in the edema paws three hours after λ-carrageenan was injected. MKGS also affected the levels of IL-1β, TNF-α and NO induced by λ-carrageenan. All these results suggested that MKGS possessed analgesic and anti-inflammatory effects. The anti-inflammatory mechanism of MKGS might be related to the lowering of MDA level in the edema paw via increasing the activities of superoxide dismutase (SOD) and GRx in the liver, as well as the decreases in the levels of TNF-α and NO, and the production of IL-1β in inflamed tissues." @default.
• W2088676196 created "2016-06-24" @default.
• W2088676196 creator A5019468863 @default.
• W2088676196 creator A5031594312 @default.
• W2088676196 creator A5031976639 @default.
• W2088676196 creator A5049976527 @default.
• W2088676196 creator A5057156357 @default.
• W2088676196 creator A5058120431 @default.
• W2088676196 creator A5063261730 @default.
• W2088676196 creator A5076402674 @default.
• W2088676196 creator A5082589980 @default.
• W2088676196 creator A5084068057 @default.
• W2088676196 date "2010-01-01" @default.
• W2088676196 modified "2023-09-24" @default.
• W2088676196 title "Analgesic and Anti-Inflammatory Activities of the Methanol Extract of<i>Kalanchoe gracilis</i>(L.) DC Stem in Mice" @default.
• W2088676196 cites W1750690213 @default.
• W2088676196 cites W1952915179 @default.
• W2088676196 cites W1967939778 @default.
• W2088676196 cites W1970652854 @default.
• W2088676196 cites W1974813927 @default.
• W2088676196 cites W1981819970 @default.
• W2088676196 cites W1987970258 @default.
• W2088676196 cites W1996716971 @default.
• W2088676196 cites W2009345240 @default.
• W2088676196 cites W2020613944 @default.
• W2088676196 cites W2023632376 @default.
• W2088676196 cites W2029190543 @default.
• W2088676196 cites W2055146579 @default.
• W2088676196 cites W2055552176 @default.
• W2088676196 cites W2055973331 @default.
• W2088676196 cites W2064175661 @default.
• W2088676196 cites W2069223457 @default.
• W2088676196 cites W2081842640 @default.
• W2088676196 cites W2085569901 @default.
• W2088676196 cites W2087454739 @default.
• W2088676196 cites W2088309420 @default.
• W2088676196 cites W2088712699 @default.
• W2088676196 cites W2089833723 @default.
• W2088676196 cites W2112487069 @default.
• W2088676196 cites W2140552199 @default.
• W2088676196 cites W2151334639 @default.
• W2088676196 cites W2156122127 @default.
• W2088676196 cites W2197332903 @default.
• W2088676196 cites W4252506458 @default.
• W2088676196 doi "https://doi.org/10.1142/s0192415x10008032" @default.
• W2088676196 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20503470" @default.
• W2088676196 hasPublicationYear "2010" @default.
• W2088676196 type Work @default.
• W2088676196 sameAs 2088676196 @default.
• W2088676196 citedByCount "16" @default.
• W2088676196 countsByYear W20886761962012 @default.
• W2088676196 countsByYear W20886761962013 @default.
• W2088676196 countsByYear W20886761962014 @default.
• W2088676196 countsByYear W20886761962016 @default.
• W2088676196 countsByYear W20886761962017 @default.
• W2088676196 countsByYear W20886761962018 @default.
• W2088676196 countsByYear W20886761962019 @default.
• W2088676196 countsByYear W20886761962020 @default.
• W2088676196 countsByYear W20886761962023 @default.
• W2088676196 crossrefType "journal-article" @default.
• W2088676196 hasAuthorship W2088676196A5019468863 @default.
• W2088676196 hasAuthorship W2088676196A5031594312 @default.
• W2088676196 hasAuthorship W2088676196A5031976639 @default.
• W2088676196 hasAuthorship W2088676196A5049976527 @default.
• W2088676196 hasAuthorship W2088676196A5057156357 @default.
• W2088676196 hasAuthorship W2088676196A5058120431 @default.
• W2088676196 hasAuthorship W2088676196A5063261730 @default.
• W2088676196 hasAuthorship W2088676196A5076402674 @default.
• W2088676196 hasAuthorship W2088676196A5082589980 @default.
• W2088676196 hasAuthorship W2088676196A5084068057 @default.
• W2088676196 hasConcept C126322002 @default.
• W2088676196 hasConcept C181199279 @default.
• W2088676196 hasConcept C185592680 @default.
• W2088676196 hasConcept C2775838275 @default.
• W2088676196 hasConcept C2778004101 @default.
• W2088676196 hasConcept C2778401633 @default.
• W2088676196 hasConcept C2778760513 @default.
• W2088676196 hasConcept C2779703632 @default.
• W2088676196 hasConcept C2780820201 @default.
• W2088676196 hasConcept C2780886150 @default.
• W2088676196 hasConcept C2781227287 @default.
• W2088676196 hasConcept C538909803 @default.
• W2088676196 hasConcept C55493867 @default.
• W2088676196 hasConcept C71924100 @default.
• W2088676196 hasConcept C98274493 @default.
• W2088676196 hasConceptScore W2088676196C126322002 @default.
• W2088676196 hasConceptScore W2088676196C181199279 @default.
• W2088676196 hasConceptScore W2088676196C185592680 @default.
• W2088676196 hasConceptScore W2088676196C2775838275 @default.
• W2088676196 hasConceptScore W2088676196C2778004101 @default.
• W2088676196 hasConceptScore W2088676196C2778401633 @default.
• W2088676196 hasConceptScore W2088676196C2778760513 @default.
• W2088676196 hasConceptScore W2088676196C2779703632 @default.
• W2088676196 hasConceptScore W2088676196C2780820201 @default.
• W2088676196 hasConceptScore W2088676196C2780886150 @default.
• W2088676196 hasConceptScore W2088676196C2781227287 @default.
• W2088676196 hasConceptScore W2088676196C538909803 @default.
• W2088676196 hasConceptScore W2088676196C55493867 @default.

• next