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- W2088748430 abstract "It has been proposed that down-regulation of beta-adrenergic receptors may be related to the therapeutic action of antidepressants. To further characterize the role of beta-adrenergic receptor regulation in the actions of antidepressants, the effects of chronic treatment with desipramine, zimelidine and bupropion on beta-adrenergic receptors in rat brain membrane preparations were studied. Chronic treatment with desipramine, but not zimelidine and bupropion decreased significantly the density of beta-adrenergic receptors. These data suggest that clinically effective antidepressants may vary considerably in their ability to down-regulate beta-adrenergic receptors after chronic treatment." @default.
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- W2088748430 date "1985-01-01" @default.
- W2088748430 modified "2023-09-29" @default.
- W2088748430 title "Variability of chronic antidepressant treatments on beta-adrenergic receptor sites" @default.
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- W2088748430 doi "https://doi.org/10.1016/0278-5846(85)90057-0" @default.
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