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- W2088768815 abstract "A report is given of a 6-year-old boy, who at 3 years of age suddenly developed signs of ataxia. Multiple eosinophilic granulomata of the bones were found, which healed on X-ray treatment. Later a spastic tetraparesis and some epileptic fits complicated the picture. At autopsy a multifocal demyelinating leuco-encephalopathy, histiocytic granulomata of the lungs and a diffuse histiocytic proliferation of the liver, spleen and thymus were found. Since a few cases of a similar demyelinating leuco-encephalopathy hare been described in combination with HandSchüller-Christian disease, a clinical variant of histiocytic reticulo-endotheliosis, this combination must be more than a coincidence and has to be taken into consideration when a patient with histiocytic reticulo-endotheliosis develops cerebral symptoms." @default.
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- W2088768815 date "1966-05-01" @default.
- W2088768815 modified "2023-09-27" @default.
- W2088768815 title "Generalized Histiocytic Reticulo-Endotheliosis and Leuco-Encephalopathy in Childhood" @default.
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- W2088768815 doi "https://doi.org/10.1111/j.1651-2227.1966.tb17661.x" @default.
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