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• W2088792337 abstract "Recently, it has become clear that herpesviruses are unique among pathogenic virus families in that they express multiple virally encoded microRNAs in latently and/or lytically infected cells. The large size and complexity of herpesvirus genomes, combined with the inability of most human herpesviruses to replicate in animals, has until recently limited our ability to examine the contribution of viral microRNAs to herpesvirus replication and pathogenesis in vivo. However, recent data, primarily obtained using model animal herpesviruses, suggest that viral microRNAs, while not required for lytic replication in culture, can nevertheless strongly enhance viral pathogenesis, including oncogenesis, in vivo and also promote the establishment of a reservoir of latently infected cells." @default.
• W2088792337 created "2016-06-24" @default.
• W2088792337 creator A5045067166 @default.
• W2088792337 date "2011-09-01" @default.
• W2088792337 modified "2023-10-07" @default.
• W2088792337 title "Herpesvirus microRNAs: phenotypes and functions" @default.
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• W2088792337 doi "https://doi.org/10.1016/j.coviro.2011.04.003" @default.
• W2088792337 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3171754" @default.
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