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• W2088887029 abstract "Modification of sulfonamid drug using different principles of chemical reactions was investigated. These reactions involve the condensation of an amino group with triethyl orthoformate and dimethylformamide dimethyl acetal. Ability of sulfa to condense with active keto compounds, like ethyl pyruvate and piprazine carboxyaldehye was studied. Alkyation of sulfa with different chloro derivatives was also reported. The structure of the isolated compound was elucidated and confirmed using elemental analysis and spectral data. The bioactivity of the ob-tained compounds was investigated against different gram positive and gram negative bacteria. The study reveals that most of the modified drugs show high to moderate antibacterial activity." @default.
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• W2088887029 date "2011-01-01" @default.
• W2088887029 modified "2023-10-16" @default.
• W2088887029 title "Synthesis, Structure Analysis and Antibacterial Activity of New Potent Sulfonamide Derivatives" @default.
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• W2088887029 doi "https://doi.org/10.4236/jbnb.2011.22018" @default.
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