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- W2088893357 abstract "A practical method for the solid-phase synthesis and purification of 14C labeled oligonucleotides is described. A streamlined procedure for the synthesis of 5′-O-dimethoxytrityl-2-(14C)-thymidine 3′-(2-cyanoethyl-N,N-diisopropyl) phosphoramidite from commercially available 2-(14C) labeled thymidine nucleoside is detailed. Methodology for the manual synthesis, isolation, and purification of a high specific activity oligonucleotide phosphorothioate 20-mer (ISIS 2105) are elaborated." @default.
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- W2088893357 date "1995-01-01" @default.
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- W2088893357 title "A practical method for the synthesis and purification of 14C labeled oligonucleotides" @default.
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- W2088893357 doi "https://doi.org/10.1002/jlcr.2580360103" @default.
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