Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088894030> ?p ?o ?g. }
- W2088894030 endingPage "404" @default.
- W2088894030 startingPage "397" @default.
- W2088894030 abstract "Biological dosimetry is an essential tool for estimating radiation dose. The dicentric chromosome assay (DCA) is currently the tool of choice. Because the assay is labor-intensive and time-consuming, strategies are needed to increase throughput for use in radiation mass casualty incidents. One such strategy is to truncate metaphase spread analysis for triage dose estimates by scoring 50 or fewer metaphases, compared to a routine analysis of 500 to 1000 metaphases, and to increase throughput using a large group of scorers in a biodosimetry network. Previously, the National Institutes for Allergies and Infectious Diseases (NIAID) and the Armed Forces Radiobiology Research Institute (AFRRI) sponsored a double-blinded interlaboratory comparison among five established international cytogenetic biodosimetry laboratories to determine the variability in calibration curves and in dose measurements in unknown, irradiated samples. In the present study, we further analyzed the published data from this previous study to investigate how the number of metaphase spreads influences dose prediction accuracy and how this information could be of value in the triage and management of people at risk for the acute radiation syndrome (ARS). Although, as expected, accuracy decreased with lower numbers of metaphase spreads analyzed, predicted doses by the laboratories were in good agreement and were judged to be adequate to guide diagnosis and treatment of ARS. These results demonstrate that for rapid triage, a network of cytogenetic biodosimetry laboratories can accurately assess doses even with a lower number of scored metaphases." @default.
- W2088894030 created "2016-06-24" @default.
- W2088894030 creator A5004485615 @default.
- W2088894030 creator A5032555890 @default.
- W2088894030 creator A5042283259 @default.
- W2088894030 creator A5048215519 @default.
- W2088894030 creator A5056908954 @default.
- W2088894030 creator A5059202876 @default.
- W2088894030 creator A5067473482 @default.
- W2088894030 creator A5071899371 @default.
- W2088894030 creator A5074511442 @default.
- W2088894030 creator A5081288251 @default.
- W2088894030 creator A5082513734 @default.
- W2088894030 date "2011-03-01" @default.
- W2088894030 modified "2023-10-01" @default.
- W2088894030 title "Biological Dosimetry by the Triage Dicentric Chromosome Assay: Potential Implications for Treatment of Acute Radiation Syndrome in Radiological Mass Casualties" @default.
- W2088894030 cites W1970750758 @default.
- W2088894030 cites W1972236668 @default.
- W2088894030 cites W1994829049 @default.
- W2088894030 cites W1999663423 @default.
- W2088894030 cites W2019866310 @default.
- W2088894030 cites W2024631621 @default.
- W2088894030 cites W2024645025 @default.
- W2088894030 cites W2052293877 @default.
- W2088894030 cites W2065263068 @default.
- W2088894030 cites W2067070260 @default.
- W2088894030 cites W2090662473 @default.
- W2088894030 cites W2092614459 @default.
- W2088894030 cites W2092926610 @default.
- W2088894030 cites W2102743607 @default.
- W2088894030 cites W2103486381 @default.
- W2088894030 cites W2107303834 @default.
- W2088894030 cites W2134010239 @default.
- W2088894030 cites W2137167619 @default.
- W2088894030 doi "https://doi.org/10.1667/rr2321.1" @default.
- W2088894030 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21388284" @default.
- W2088894030 hasPublicationYear "2011" @default.
- W2088894030 type Work @default.
- W2088894030 sameAs 2088894030 @default.
- W2088894030 citedByCount "65" @default.
- W2088894030 countsByYear W20888940302012 @default.
- W2088894030 countsByYear W20888940302013 @default.
- W2088894030 countsByYear W20888940302014 @default.
- W2088894030 countsByYear W20888940302015 @default.
- W2088894030 countsByYear W20888940302016 @default.
- W2088894030 countsByYear W20888940302017 @default.
- W2088894030 countsByYear W20888940302018 @default.
- W2088894030 countsByYear W20888940302019 @default.
- W2088894030 countsByYear W20888940302020 @default.
- W2088894030 countsByYear W20888940302021 @default.
- W2088894030 countsByYear W20888940302022 @default.
- W2088894030 countsByYear W20888940302023 @default.
- W2088894030 crossrefType "journal-article" @default.
- W2088894030 hasAuthorship W2088894030A5004485615 @default.
- W2088894030 hasAuthorship W2088894030A5032555890 @default.
- W2088894030 hasAuthorship W2088894030A5042283259 @default.
- W2088894030 hasAuthorship W2088894030A5048215519 @default.
- W2088894030 hasAuthorship W2088894030A5056908954 @default.
- W2088894030 hasAuthorship W2088894030A5059202876 @default.
- W2088894030 hasAuthorship W2088894030A5067473482 @default.
- W2088894030 hasAuthorship W2088894030A5071899371 @default.
- W2088894030 hasAuthorship W2088894030A5074511442 @default.
- W2088894030 hasAuthorship W2088894030A5081288251 @default.
- W2088894030 hasAuthorship W2088894030A5082513734 @default.
- W2088894030 hasConcept C103037022 @default.
- W2088894030 hasConcept C104317684 @default.
- W2088894030 hasConcept C111337013 @default.
- W2088894030 hasConcept C121332964 @default.
- W2088894030 hasConcept C141071460 @default.
- W2088894030 hasConcept C18231593 @default.
- W2088894030 hasConcept C185544564 @default.
- W2088894030 hasConcept C190892606 @default.
- W2088894030 hasConcept C194828623 @default.
- W2088894030 hasConcept C19527891 @default.
- W2088894030 hasConcept C2777120189 @default.
- W2088894030 hasConcept C2779254040 @default.
- W2088894030 hasConcept C2908818428 @default.
- W2088894030 hasConcept C2989005 @default.
- W2088894030 hasConcept C30481170 @default.
- W2088894030 hasConcept C53226629 @default.
- W2088894030 hasConcept C54355233 @default.
- W2088894030 hasConcept C545542383 @default.
- W2088894030 hasConcept C70278784 @default.
- W2088894030 hasConcept C71924100 @default.
- W2088894030 hasConcept C75088862 @default.
- W2088894030 hasConcept C86803240 @default.
- W2088894030 hasConceptScore W2088894030C103037022 @default.
- W2088894030 hasConceptScore W2088894030C104317684 @default.
- W2088894030 hasConceptScore W2088894030C111337013 @default.
- W2088894030 hasConceptScore W2088894030C121332964 @default.
- W2088894030 hasConceptScore W2088894030C141071460 @default.
- W2088894030 hasConceptScore W2088894030C18231593 @default.
- W2088894030 hasConceptScore W2088894030C185544564 @default.
- W2088894030 hasConceptScore W2088894030C190892606 @default.
- W2088894030 hasConceptScore W2088894030C194828623 @default.
- W2088894030 hasConceptScore W2088894030C19527891 @default.
- W2088894030 hasConceptScore W2088894030C2777120189 @default.
- W2088894030 hasConceptScore W2088894030C2779254040 @default.