FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088894758> ?p ?o ?g. }

• W2088894758 endingPage "284" @default.
• W2088894758 startingPage "278" @default.
• W2088894758 abstract "Direct protein delivery is an emerging technology in vaccine development and gene therapy. We could previously show that subviral dense bodies (DB) of human cytomegalovirus (HCMV), a beta-herpesvirus, transport viral proteins into target cells by membrane fusion. Thus these non-infectious particles provide a candidate delivery system for the prophylactic and therapeutic application of proteins. Here we provide proof of principle that DB can be modified genetically. A 55 kDa fusion protein consisting of the green fluorescent protein and the neomycin phosphotransferase could be packed in and delivered into cells by recombinant DB in a functional fashion. Furthermore, transfer of protein into fibroblasts and dendritic cells by DB was efficient, leading to exogenous loading of the MHC-class I antigen presentation pathway. Thus, DB may be a promising basis for the development of novel vaccine strategies and therapeutics based on recombinant polypeptides." @default.
• W2088894758 created "2016-06-24" @default.
• W2088894758 creator A5004777692 @default.
• W2088894758 creator A5054227288 @default.
• W2088894758 creator A5055446460 @default.
• W2088894758 creator A5071342523 @default.
• W2088894758 date "2003-01-23" @default.
• W2088894758 modified "2023-09-27" @default.
• W2088894758 title "Protein delivery by subviral particles of human cytomegalovirus" @default.
• W2088894758 cites W1493317439 @default.
• W2088894758 cites W1577743463 @default.
• W2088894758 cites W1663973802 @default.
• W2088894758 cites W1970973269 @default.
• W2088894758 cites W1992390228 @default.
• W2088894758 cites W1995981086 @default.
• W2088894758 cites W2022549031 @default.
• W2088894758 cites W2029794523 @default.
• W2088894758 cites W2032092033 @default.
• W2088894758 cites W2038720675 @default.
• W2088894758 cites W2039344241 @default.
• W2088894758 cites W2050784170 @default.
• W2088894758 cites W2064975687 @default.
• W2088894758 cites W2071056869 @default.
• W2088894758 cites W2076859770 @default.
• W2088894758 cites W2077721338 @default.
• W2088894758 cites W2079335891 @default.
• W2088894758 cites W2085105126 @default.
• W2088894758 cites W2089657872 @default.
• W2088894758 cites W2096002663 @default.
• W2088894758 cites W2099985438 @default.
• W2088894758 cites W2105668301 @default.
• W2088894758 cites W2115855421 @default.
• W2088894758 cites W2124489120 @default.
• W2088894758 cites W2131761283 @default.
• W2088894758 cites W2145687844 @default.
• W2088894758 cites W2159305020 @default.
• W2088894758 cites W2164339006 @default.
• W2088894758 cites W2168235758 @default.
• W2088894758 cites W2262757894 @default.
• W2088894758 cites W2320515801 @default.
• W2088894758 doi "https://doi.org/10.1038/sj.gt.3301879" @default.
• W2088894758 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12571636" @default.
• W2088894758 hasPublicationYear "2003" @default.
• W2088894758 type Work @default.
• W2088894758 sameAs 2088894758 @default.
• W2088894758 citedByCount "23" @default.
• W2088894758 countsByYear W20888947582012 @default.
• W2088894758 countsByYear W20888947582013 @default.
• W2088894758 countsByYear W20888947582014 @default.
• W2088894758 countsByYear W20888947582019 @default.
• W2088894758 countsByYear W20888947582021 @default.
• W2088894758 countsByYear W20888947582022 @default.
• W2088894758 crossrefType "journal-article" @default.
• W2088894758 hasAuthorship W2088894758A5004777692 @default.
• W2088894758 hasAuthorship W2088894758A5054227288 @default.
• W2088894758 hasAuthorship W2088894758A5055446460 @default.
• W2088894758 hasAuthorship W2088894758A5071342523 @default.
• W2088894758 hasBestOaLocation W20888947581 @default.
• W2088894758 hasConcept C104317684 @default.
• W2088894758 hasConcept C111599444 @default.
• W2088894758 hasConcept C123894998 @default.
• W2088894758 hasConcept C135983454 @default.
• W2088894758 hasConcept C142613039 @default.
• W2088894758 hasConcept C147483822 @default.
• W2088894758 hasConcept C159047783 @default.
• W2088894758 hasConcept C170627219 @default.
• W2088894758 hasConcept C203014093 @default.
• W2088894758 hasConcept C207936829 @default.
• W2088894758 hasConcept C2522874641 @default.
• W2088894758 hasConcept C2776409557 @default.
• W2088894758 hasConcept C2777732132 @default.
• W2088894758 hasConcept C2779820661 @default.
• W2088894758 hasConcept C2780727368 @default.
• W2088894758 hasConcept C32470452 @default.
• W2088894758 hasConcept C40767141 @default.
• W2088894758 hasConcept C54009773 @default.
• W2088894758 hasConcept C55493867 @default.
• W2088894758 hasConcept C86803240 @default.
• W2088894758 hasConcept C95444343 @default.
• W2088894758 hasConceptScore W2088894758C104317684 @default.
• W2088894758 hasConceptScore W2088894758C111599444 @default.
• W2088894758 hasConceptScore W2088894758C123894998 @default.
• W2088894758 hasConceptScore W2088894758C135983454 @default.
• W2088894758 hasConceptScore W2088894758C142613039 @default.
• W2088894758 hasConceptScore W2088894758C147483822 @default.
• W2088894758 hasConceptScore W2088894758C159047783 @default.
• W2088894758 hasConceptScore W2088894758C170627219 @default.
• W2088894758 hasConceptScore W2088894758C203014093 @default.
• W2088894758 hasConceptScore W2088894758C207936829 @default.
• W2088894758 hasConceptScore W2088894758C2522874641 @default.
• W2088894758 hasConceptScore W2088894758C2776409557 @default.
• W2088894758 hasConceptScore W2088894758C2777732132 @default.
• W2088894758 hasConceptScore W2088894758C2779820661 @default.
• W2088894758 hasConceptScore W2088894758C2780727368 @default.
• W2088894758 hasConceptScore W2088894758C32470452 @default.
• W2088894758 hasConceptScore W2088894758C40767141 @default.
• W2088894758 hasConceptScore W2088894758C54009773 @default.
• W2088894758 hasConceptScore W2088894758C55493867 @default.

• next