Matches in SemOpenAlex for { <https://semopenalex.org/work/W2088958397> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2088958397 endingPage "1828" @default.
- W2088958397 startingPage "1825" @default.
- W2088958397 abstract "Cerebral cavernous malformation (CCM) is one of the most common vascular malformations of the CNS. Familial CCM are increasingly diagnosed, but little is known about their natural history, especially in asymptomatic patients.To determine the degree of spontaneous evolution of familial CCM in a population of 33 symptom-free patients.During a previous national survey, the authors analyzed the clinical and MRI features of 173 patients from 57 unrelated French families, including 73 asymptomatic subjects. Of these 73 subjects, 33 prospectively underwent two serial clinical and MRI examinations. Cerebral MRI systematically included spin echo and gradient echo sequences. Occurrence of clinical symptoms and MRI changes of CCM, namely, hemorrhage, change in signal intensity, change in size, and appearance of new lesions, were recorded by means of comparison of the first and last MRI examinations.The 33 patients (234 CCM, mean 7.1 lesions/subject, range 1 to 85 lesions/subject) were followed during a mean period of 2.1 years (range 0.5 to 4.5 years). Two patients became symptomatic: One presented with brainstem hemorrhage and one with partial seizure. Comparison of the two serial MR images found changes in 15 patients (46%): 1) Bleeding occurred in three type II lesions (1.3%) in three patients (9.1%); 2) 30 new lesions appeared in 10 patients (30.3%); 3) change in signal intensity was observed in one lesion (0.4%) in one patient (3%); and 4) increase in size was observed in four lesions (1.7%) in three patients (9.1%).This prospective study confirms the dynamic nature of CCM. The appearance of new lesions in 30% of patients has to be retained as a hallmark of the familial condition." @default.
- W2088958397 created "2016-06-24" @default.
- W2088958397 creator A5009282279 @default.
- W2088958397 creator A5010092850 @default.
- W2088958397 creator A5034052926 @default.
- W2088958397 creator A5084820926 @default.
- W2088958397 date "2001-11-27" @default.
- W2088958397 modified "2023-09-25" @default.
- W2088958397 title "Prospective follow-up of 33 asymptomatic patients with familial cerebral cavernous malformations" @default.
- W2088958397 cites W1608253138 @default.
- W2088958397 cites W1963865515 @default.
- W2088958397 cites W1964707962 @default.
- W2088958397 cites W1978747030 @default.
- W2088958397 cites W1991860914 @default.
- W2088958397 cites W1991872394 @default.
- W2088958397 cites W2034537149 @default.
- W2088958397 cites W2038611147 @default.
- W2088958397 cites W2051691391 @default.
- W2088958397 cites W2055454171 @default.
- W2088958397 cites W2058735256 @default.
- W2088958397 cites W2121850322 @default.
- W2088958397 cites W2147783244 @default.
- W2088958397 cites W2152071621 @default.
- W2088958397 cites W2157638088 @default.
- W2088958397 cites W2157863903 @default.
- W2088958397 cites W2167210272 @default.
- W2088958397 cites W2168442041 @default.
- W2088958397 cites W3025310816 @default.
- W2088958397 cites W2346345732 @default.
- W2088958397 doi "https://doi.org/10.1212/wnl.57.10.1825" @default.
- W2088958397 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11723271" @default.
- W2088958397 hasPublicationYear "2001" @default.
- W2088958397 type Work @default.
- W2088958397 sameAs 2088958397 @default.
- W2088958397 citedByCount "120" @default.
- W2088958397 countsByYear W20889583972012 @default.
- W2088958397 countsByYear W20889583972013 @default.
- W2088958397 countsByYear W20889583972014 @default.
- W2088958397 countsByYear W20889583972015 @default.
- W2088958397 countsByYear W20889583972016 @default.
- W2088958397 countsByYear W20889583972017 @default.
- W2088958397 countsByYear W20889583972018 @default.
- W2088958397 countsByYear W20889583972019 @default.
- W2088958397 countsByYear W20889583972020 @default.
- W2088958397 countsByYear W20889583972021 @default.
- W2088958397 countsByYear W20889583972022 @default.
- W2088958397 countsByYear W20889583972023 @default.
- W2088958397 crossrefType "journal-article" @default.
- W2088958397 hasAuthorship W2088958397A5009282279 @default.
- W2088958397 hasAuthorship W2088958397A5010092850 @default.
- W2088958397 hasAuthorship W2088958397A5034052926 @default.
- W2088958397 hasAuthorship W2088958397A5084820926 @default.
- W2088958397 hasConcept C126322002 @default.
- W2088958397 hasConcept C126838900 @default.
- W2088958397 hasConcept C141071460 @default.
- W2088958397 hasConcept C143409427 @default.
- W2088958397 hasConcept C163276114 @default.
- W2088958397 hasConcept C188816634 @default.
- W2088958397 hasConcept C2777910003 @default.
- W2088958397 hasConcept C2779756704 @default.
- W2088958397 hasConcept C2781156865 @default.
- W2088958397 hasConcept C2908647359 @default.
- W2088958397 hasConcept C71924100 @default.
- W2088958397 hasConcept C99454951 @default.
- W2088958397 hasConceptScore W2088958397C126322002 @default.
- W2088958397 hasConceptScore W2088958397C126838900 @default.
- W2088958397 hasConceptScore W2088958397C141071460 @default.
- W2088958397 hasConceptScore W2088958397C143409427 @default.
- W2088958397 hasConceptScore W2088958397C163276114 @default.
- W2088958397 hasConceptScore W2088958397C188816634 @default.
- W2088958397 hasConceptScore W2088958397C2777910003 @default.
- W2088958397 hasConceptScore W2088958397C2779756704 @default.
- W2088958397 hasConceptScore W2088958397C2781156865 @default.
- W2088958397 hasConceptScore W2088958397C2908647359 @default.
- W2088958397 hasConceptScore W2088958397C71924100 @default.
- W2088958397 hasConceptScore W2088958397C99454951 @default.
- W2088958397 hasIssue "10" @default.
- W2088958397 hasLocation W20889583971 @default.
- W2088958397 hasLocation W20889583972 @default.
- W2088958397 hasOpenAccess W2088958397 @default.
- W2088958397 hasPrimaryLocation W20889583971 @default.
- W2088958397 hasRelatedWork W1995188757 @default.
- W2088958397 hasRelatedWork W1998535992 @default.
- W2088958397 hasRelatedWork W2016679923 @default.
- W2088958397 hasRelatedWork W2056378237 @default.
- W2088958397 hasRelatedWork W2067277807 @default.
- W2088958397 hasRelatedWork W2116001782 @default.
- W2088958397 hasRelatedWork W2159322525 @default.
- W2088958397 hasRelatedWork W2400727047 @default.
- W2088958397 hasRelatedWork W2414604743 @default.
- W2088958397 hasRelatedWork W4229900919 @default.
- W2088958397 hasVolume "57" @default.
- W2088958397 isParatext "false" @default.
- W2088958397 isRetracted "false" @default.
- W2088958397 magId "2088958397" @default.
- W2088958397 workType "article" @default.