FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2089085348> ?p ?o ?g. }

• W2089085348 endingPage "259" @default.
• W2089085348 startingPage "250" @default.
• W2089085348 abstract "A previous report described a prime-boost immunization strategy using plasmid and modified vaccinia virus Ankara (MVA) vectors expressing herpes simplex virus 2 glycoprotein D (gD). Enhanced humoral and cellular immune responses were elicited by the prime-boost combination compared to plasmid DNA immunization alone. Surprisingly, a more diverse antibody isotype response, and a greater antibody and cellular immune response, was obtained if the gD MVA vector was used as the priming immunization rather than the gD plasmid vector. The present report evaluates the use of a needle-free delivery platform (Biojector) for delivery of plasmid and MVA gD-expressing vectors in a prime-boost immunization strategy. Needle-free delivery of both plasmid and MVA gD expression vectors was efficient, reproducible, and elicited a strong immune response in immunized mice. Biojector delivery of plasmid DNA was able to evoke a broader isotype response and cellular immune response than that obtained by gene gun delivered plasmid DNA. Further, DNA priming by Biojector delivery as part of a prime-boost procedure with MVA-gD2 resulted in a diverse antibody isotype distribution and enhanced cellular immune responses, similar to the responses obtained when MVA-gD2 was used as the priming immunization. Thus, needle-free delivery of plasmid DNA may provide additional flexibility and options for effective prime-boost vaccination." @default.
• W2089085348 created "2016-06-24" @default.
• W2089085348 creator A5037681029 @default.
• W2089085348 creator A5050118443 @default.
• W2089085348 creator A5056199486 @default.
• W2089085348 date "2006-06-01" @default.
• W2089085348 modified "2023-09-27" @default.
• W2089085348 title "Evaluation of a Needle-Free Delivery Platform for Prime-Boost Immunization with DNA and Modified Vaccinia Virus Ankara Vectors Expressing Herpes Simplex Virus 2 Glycoprotein D" @default.
• W2089085348 cites W1969352328 @default.
• W2089085348 cites W1976215218 @default.
• W2089085348 cites W1981552834 @default.
• W2089085348 cites W2002022916 @default.
• W2089085348 cites W2002167432 @default.
• W2089085348 cites W2003207270 @default.
• W2089085348 cites W2003627888 @default.
• W2089085348 cites W2012518985 @default.
• W2089085348 cites W2023976368 @default.
• W2089085348 cites W2038042144 @default.
• W2089085348 cites W2040865227 @default.
• W2089085348 cites W2045721815 @default.
• W2089085348 cites W2065157516 @default.
• W2089085348 cites W2068133624 @default.
• W2089085348 cites W2078685026 @default.
• W2089085348 cites W2080066257 @default.
• W2089085348 cites W2101702353 @default.
• W2089085348 cites W2102554240 @default.
• W2089085348 cites W2109237259 @default.
• W2089085348 cites W2129226474 @default.
• W2089085348 cites W2137538149 @default.
• W2089085348 cites W2146028208 @default.
• W2089085348 cites W2159465958 @default.
• W2089085348 cites W2167176207 @default.
• W2089085348 cites W2184646877 @default.
• W2089085348 cites W4252259151 @default.
• W2089085348 doi "https://doi.org/10.1089/vim.2006.19.250" @default.
• W2089085348 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16817767" @default.
• W2089085348 hasPublicationYear "2006" @default.
• W2089085348 type Work @default.
• W2089085348 sameAs 2089085348 @default.
• W2089085348 citedByCount "20" @default.
• W2089085348 countsByYear W20890853482012 @default.
• W2089085348 countsByYear W20890853482013 @default.
• W2089085348 countsByYear W20890853482014 @default.
• W2089085348 countsByYear W20890853482015 @default.
• W2089085348 countsByYear W20890853482016 @default.
• W2089085348 countsByYear W20890853482020 @default.
• W2089085348 countsByYear W20890853482021 @default.
• W2089085348 crossrefType "journal-article" @default.
• W2089085348 hasAuthorship W2089085348A5037681029 @default.
• W2089085348 hasAuthorship W2089085348A5050118443 @default.
• W2089085348 hasAuthorship W2089085348A5056199486 @default.
• W2089085348 hasConcept C100701293 @default.
• W2089085348 hasConcept C104317684 @default.
• W2089085348 hasConcept C111599444 @default.
• W2089085348 hasConcept C135983454 @default.
• W2089085348 hasConcept C159047783 @default.
• W2089085348 hasConcept C167508917 @default.
• W2089085348 hasConcept C203014093 @default.
• W2089085348 hasConcept C22744801 @default.
• W2089085348 hasConcept C2522874641 @default.
• W2089085348 hasConcept C2777760223 @default.
• W2089085348 hasConcept C2780801004 @default.
• W2089085348 hasConcept C2781196997 @default.
• W2089085348 hasConcept C2781356689 @default.
• W2089085348 hasConcept C40767141 @default.
• W2089085348 hasConcept C54355233 @default.
• W2089085348 hasConcept C552990157 @default.
• W2089085348 hasConcept C59822182 @default.
• W2089085348 hasConcept C81444415 @default.
• W2089085348 hasConcept C86803240 @default.
• W2089085348 hasConcept C8891405 @default.
• W2089085348 hasConcept C92087593 @default.
• W2089085348 hasConceptScore W2089085348C100701293 @default.
• W2089085348 hasConceptScore W2089085348C104317684 @default.
• W2089085348 hasConceptScore W2089085348C111599444 @default.
• W2089085348 hasConceptScore W2089085348C135983454 @default.
• W2089085348 hasConceptScore W2089085348C159047783 @default.
• W2089085348 hasConceptScore W2089085348C167508917 @default.
• W2089085348 hasConceptScore W2089085348C203014093 @default.
• W2089085348 hasConceptScore W2089085348C22744801 @default.
• W2089085348 hasConceptScore W2089085348C2522874641 @default.
• W2089085348 hasConceptScore W2089085348C2777760223 @default.
• W2089085348 hasConceptScore W2089085348C2780801004 @default.
• W2089085348 hasConceptScore W2089085348C2781196997 @default.
• W2089085348 hasConceptScore W2089085348C2781356689 @default.
• W2089085348 hasConceptScore W2089085348C40767141 @default.
• W2089085348 hasConceptScore W2089085348C54355233 @default.
• W2089085348 hasConceptScore W2089085348C552990157 @default.
• W2089085348 hasConceptScore W2089085348C59822182 @default.
• W2089085348 hasConceptScore W2089085348C81444415 @default.
• W2089085348 hasConceptScore W2089085348C86803240 @default.
• W2089085348 hasConceptScore W2089085348C8891405 @default.
• W2089085348 hasConceptScore W2089085348C92087593 @default.
• W2089085348 hasIssue "2" @default.
• W2089085348 hasLocation W20890853481 @default.
• W2089085348 hasLocation W20890853482 @default.
• W2089085348 hasOpenAccess W2089085348 @default.
• W2089085348 hasPrimaryLocation W20890853481 @default.

• next