FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2089222132> ?p ?o ?g. }

• W2089222132 endingPage "491" @default.
• W2089222132 startingPage "485" @default.
• W2089222132 abstract "Dendritic cells (DCs) are thought to play an important role in the pathogenesis of allergic disorders through their ability to interact with T cells to initiate and amplify helper T cell Type 2 immune responses. The mechanisms by which this occurs are not completely understood, nor is it clear whether DC function differs between normal individuals and individuals with asthma. We compared the function of DCs from 10 subjects with allergic asthma and 10 normal individuals, focusing on the production of prostaglandin E (PGE) 2, interleukin (IL)-10, and IL-12 p70, mediators that play an important role in helper T cell Type 1/Type 2 polarization. Monocyte-derived DCs were established by culturing monocytes with granulocyte-macrophage colony-stimulating factor and IL-4 for 7 days, and then stimulated with LPS plus IFN-γ. PGE2, IL-10, and IL-12 production was evaluated by ELISA, whereas cyclooxygenase-1, and -2 messenger RNA expression was analyzed using reverse transcription-polymerase chain reaction. LPS-stimulated monocyte-derived DCs from individuals with asthma exhibited increased PGE2 and IL-10 production, but equivalent IL-12 p70 synthesis, when compared with DCs from normal subjects. Increased PGE2 synthesis by DCs from subjects with asthma was associated with an increase in cyclooxygenase-2 messenger RNA expression. These findings support the notion that DC function is significantly altered in allergic asthma." @default.
• W2089222132 created "2016-06-24" @default.
• W2089222132 creator A5030526109 @default.
• W2089222132 creator A5034265370 @default.
• W2089222132 creator A5035806248 @default.
• W2089222132 creator A5040255306 @default.
• W2089222132 creator A5069849291 @default.
• W2089222132 date "2004-09-01" @default.
• W2089222132 modified "2023-09-23" @default.
• W2089222132 title "Higher Prostaglandin E2 Production by Dendritic Cells from Subjects with Asthma Compared with Normal Subjects" @default.
• W2089222132 cites W1498671792 @default.
• W2089222132 cites W1518494454 @default.
• W2089222132 cites W1530122683 @default.
• W2089222132 cites W1532147512 @default.
• W2089222132 cites W1568945049 @default.
• W2089222132 cites W1579010799 @default.
• W2089222132 cites W1647832452 @default.
• W2089222132 cites W1713856372 @default.
• W2089222132 cites W1769928764 @default.
• W2089222132 cites W1970846519 @default.
• W2089222132 cites W1974912313 @default.
• W2089222132 cites W1976041595 @default.
• W2089222132 cites W1979655911 @default.
• W2089222132 cites W1983865870 @default.
• W2089222132 cites W1990458269 @default.
• W2089222132 cites W1991794670 @default.
• W2089222132 cites W2007245569 @default.
• W2089222132 cites W2007470727 @default.
• W2089222132 cites W2025926163 @default.
• W2089222132 cites W2029941300 @default.
• W2089222132 cites W2033172475 @default.
• W2089222132 cites W2036963336 @default.
• W2089222132 cites W2043741373 @default.
• W2089222132 cites W2044763085 @default.
• W2089222132 cites W2053163556 @default.
• W2089222132 cites W2055923354 @default.
• W2089222132 cites W2064652856 @default.
• W2089222132 cites W2070922418 @default.
• W2089222132 cites W2075339892 @default.
• W2089222132 cites W2076146107 @default.
• W2089222132 cites W2087151532 @default.
• W2089222132 cites W2093713190 @default.
• W2089222132 cites W2099289777 @default.
• W2089222132 cites W2103179149 @default.
• W2089222132 cites W2105735510 @default.
• W2089222132 cites W2117891493 @default.
• W2089222132 cites W2120930368 @default.
• W2089222132 cites W2126615361 @default.
• W2089222132 cites W2133162139 @default.
• W2089222132 cites W2133449559 @default.
• W2089222132 cites W2134204376 @default.
• W2089222132 cites W2140117437 @default.
• W2089222132 cites W2142583764 @default.
• W2089222132 cites W2146208666 @default.
• W2089222132 cites W2151906691 @default.
• W2089222132 cites W2152044788 @default.
• W2089222132 cites W2155963054 @default.
• W2089222132 cites W2162368140 @default.
• W2089222132 cites W2163818260 @default.
• W2089222132 cites W2166650828 @default.
• W2089222132 cites W2301237480 @default.
• W2089222132 cites W4233481128 @default.
• W2089222132 cites W4243641777 @default.
• W2089222132 doi "https://doi.org/10.1164/rccm.200311-1595oc" @default.
• W2089222132 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15151923" @default.
• W2089222132 hasPublicationYear "2004" @default.
• W2089222132 type Work @default.
• W2089222132 sameAs 2089222132 @default.
• W2089222132 citedByCount "27" @default.
• W2089222132 countsByYear W20892221322012 @default.
• W2089222132 countsByYear W20892221322013 @default.
• W2089222132 countsByYear W20892221322014 @default.
• W2089222132 countsByYear W20892221322016 @default.
• W2089222132 countsByYear W20892221322018 @default.
• W2089222132 crossrefType "journal-article" @default.
• W2089222132 hasAuthorship W2089222132A5030526109 @default.
• W2089222132 hasAuthorship W2089222132A5034265370 @default.
• W2089222132 hasAuthorship W2089222132A5035806248 @default.
• W2089222132 hasAuthorship W2089222132A5040255306 @default.
• W2089222132 hasAuthorship W2089222132A5069849291 @default.
• W2089222132 hasConcept C134018914 @default.
• W2089222132 hasConcept C203014093 @default.
• W2089222132 hasConcept C2776042228 @default.
• W2089222132 hasConcept C2776090121 @default.
• W2089222132 hasConcept C2777956040 @default.
• W2089222132 hasConcept C2778170410 @default.
• W2089222132 hasConcept C2781136212 @default.
• W2089222132 hasConcept C2781184567 @default.
• W2089222132 hasConcept C71924100 @default.
• W2089222132 hasConcept C8891405 @default.
• W2089222132 hasConceptScore W2089222132C134018914 @default.
• W2089222132 hasConceptScore W2089222132C203014093 @default.
• W2089222132 hasConceptScore W2089222132C2776042228 @default.
• W2089222132 hasConceptScore W2089222132C2776090121 @default.
• W2089222132 hasConceptScore W2089222132C2777956040 @default.
• W2089222132 hasConceptScore W2089222132C2778170410 @default.
• W2089222132 hasConceptScore W2089222132C2781136212 @default.
• W2089222132 hasConceptScore W2089222132C2781184567 @default.

• next