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- W2089288966 abstract "The sodium contents of beta-cell-rich pancreatic islets from ob/ob-mice were measured with an integrating flame photometer. After washing to an apparent steady state with different types of ice-cold media, islets incubated in the absence of glucose contained 79-108 mmol sodium kg-1 dry weight. Exposure to glucose resulted in 25% reduction of the islet content of sodium. This effect became manifest in the presence of 5 mM glucose, there being no additional reduction with a further increase of glucose to 20 mM. Depression of Na+ activity may partially explain why glucose, under certain conditions, can lower cytoplasmic Ca2+ and even inhibit insulin release." @default.
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- W2089288966 date "1986-11-01" @default.
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- W2089288966 title "Glucose-induced reduction of the sodium content in β-cell-rich pancreatic islets" @default.
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- W2089288966 doi "https://doi.org/10.1007/bf01114973" @default.
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