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- W2089358066 abstract "A convergent biomimetic synthesis of hemibrevetoxin B from d-glucal and d-arabinose utilizes an electrophile-promoted cascade anti-Baldwin cyclization of an epoxy alcohol. The epoxy alcohol arises from a palladium-catalyzed coupling of a highly functionalized organozinc compound and an alkenyl iodide, which serve as two chiral building blocks of similar size and complexity. This first successful implementation of a cascade epoxy alcohol cyclization for the synthesis of marine polycyclic ether toxins proceeds in 39 steps and 4% overall yield." @default.
- W2089358066 created "2016-06-24" @default.
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- W2089358066 date "2003-06-06" @default.
- W2089358066 modified "2023-10-03" @default.
- W2089358066 title "A Convergent Total Synthesis of Hemibrevetoxin B" @default.
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- W2089358066 doi "https://doi.org/10.1021/ja029225v" @default.
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