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- W2089362912 abstract "The use of aspirin and clopidogrel in combination has become part of the standard clinical care of patients with coronary artery disease. The use of this combination provides significant benefits compared with the use of aspirin alone in patients with acute coronary syndromes, and in patients treated with percutaneous coronary intervention with stent placement (both bare metal and drug-eluting stents). Clinical trials have demonstrated significant efficacy of this dual therapy; however, there is the potential for significant bleeding complications from the synergistic antiplatelet effects. In total, it appears that when there is vessel injury (mechanical from perctutaneous coronary intervention or a ruptured plaque), dual antiplatelet therapy with aspirin and clopidogrel results in improved outcomes, albeit with a small but significant inherent risk of increased bleeding." @default.
- W2089362912 created "2016-06-24" @default.
- W2089362912 creator A5060576956 @default.
- W2089362912 creator A5079685011 @default.
- W2089362912 date "2006-10-18" @default.
- W2089362912 modified "2023-10-14" @default.
- W2089362912 title "The safety and efficacy of aspirin and clopidogrel as a combination treatment in patients with coronary heart disease" @default.
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- W2089362912 doi "https://doi.org/10.1517/14740338.5.6.815" @default.
- W2089362912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17044808" @default.
- W2089362912 hasPublicationYear "2006" @default.
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