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- W2089367050 abstract "To investigate whether narrow band imaging (NBI) is a useful tool for the in vivo detection of angiogenesis in inflammatory bowel disease (IBD) patients.Conventional and NBI colonoscopy was performed in 14 patients with colonic inflammation (8 ulcerative colitis and 6 Crohn's disease). Biopsy samples were taken and CD31 expression was assayed immunohistochemically; microvascular density was assessed by vessel count.In areas that were endoscopically normal but positive on NBI, there was a significant (P < 0.05) increase in angiogenesis (12 +/- 1 vessels/field vs 18 +/- 2 vessels/field) compared with areas negative on NBI. In addition, in areas that were inflamed on white light endoscopy and positive on NBI, there was a significant (P < 0.01) increase in vessel density (24 +/- 7 vessels/field) compared with NBI-negative areas.NBI may allow in vivo imaging of intestinal angiogenesis in IBD patients." @default.
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- W2089367050 date "2010-01-01" @default.
- W2089367050 modified "2023-09-30" @default.
- W2089367050 title "Narrow-band imaging endoscopy to assess mucosal angiogenesis in inflammatory bowel disease: A pilot study" @default.
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- W2089367050 doi "https://doi.org/10.3748/wjg.v16.i19.2396" @default.
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