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• W2089418131 abstract "Using immunofluorescence microscopy and two-dimensional gel electrophoresis, we compared the cytoskeletal proteins expressed by human amnion epithelium in situ, obtained from pregnancies of from 10-wk to birth, with the corresponding proteins from cultured amnion epithelial cells and cultures of cells from the amniotic fluid of 16 week pregnancies. Epithelia of week 16 fetuses already display tissue-specific patterns of cytokeratin polypeptides which are similar, although not identical, to those of the corresponding adult tissues. In the case of the simple amnion epithelium, a complex and characteristic complement of cytokeratin polypeptides of Mr 58,000 (No. 5), 56,000 (No. 6), 54,000 (No. 7), 52,500 (No. 8), 50,000 (No. 14), 46,000 (No. 17), 45,000 (No. 18), and 40,000 (No. 19) is present by week 10 of pregnancy and is essentially maintained until birth, with the addition of cytokeratin No. 4 (Mr 59,000) and the disappearance of No. 7 (Mr 54,000) at week 16 of pregnancy. In full-term placentae, the amnion epithelium displays two morphologically distinct regions, i.e., a simple and a stratified epithelium, both of which express the typical amnion cytokeratin polypeptides. However, in addition the stratified epithelium also synthesizes large amounts of special epidermal cytokeratins such as No. 1 (Mr 68,000), 10 (Mr 56,500), and 11 (Mr 56,000). In culture amnion epithelial cells obtained from either 16-wk pregnancies or full-term placentae will continue to synthesize the amnion-typical cytokeratin pattern, except for a loss of detection of component No. 4. This pattern is considerably different from the cytokeratins synthesized by cultures of cells from amniotic fluids (cytokeratins No. 7, 8, 18, and 19, sometimes with trace amounts of No. 17) and from several so-called amnion epithelial cell lines. In addition, amnion epithelial cells in situ as well as amnion epithelial cell cultures appear to be heterogeneous in that they possess some cells that co-express cytokeratins and vimentin. These observations lead to several important conclusions: In contrast to the general concept of recent literature, positively charged cytokeratins of the group No. 4-6 can be synthesized in a simple, i.e., one-layered epithelium. The change from simple to stratified amnion epithelium does not require a cessation of synthesis of cytokeratins of the simple epithelium type, but in this case keratins characteristic of the terminally differentiated epidermis (No. 1, 10, and 11) are also synthesized.(ABSTRACT TRUNCATED AT 400 WORDS)" @default.
• W2089418131 created "2016-06-24" @default.
• W2089418131 creator A5006736868 @default.
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• W2089418131 date "1985-04-01" @default.
• W2089418131 modified "2023-10-15" @default.
• W2089418131 title "Intermediate filament cytoskeleton of amnion epithelium and cultured amnion epithelial cells: expression of epidermal cytokeratins in cells of a simple epithelium." @default.
• W2089418131 cites W1516227994 @default.
• W2089418131 cites W1519345765 @default.
• W2089418131 cites W1579523891 @default.
• W2089418131 cites W1581322996 @default.
• W2089418131 cites W1583233593 @default.
• W2089418131 cites W1594237786 @default.
• W2089418131 cites W1606423922 @default.
• W2089418131 cites W161386972 @default.
• W2089418131 cites W1871140207 @default.
• W2089418131 cites W188486901 @default.
• W2089418131 cites W1935886529 @default.
• W2089418131 cites W1965048491 @default.
• W2089418131 cites W1965386826 @default.
• W2089418131 cites W1967233045 @default.
• W2089418131 cites W1967358782 @default.
• W2089418131 cites W1973869185 @default.
• W2089418131 cites W1980216307 @default.
• W2089418131 cites W1980429073 @default.
• W2089418131 cites W1980755114 @default.
• W2089418131 cites W1982235561 @default.
• W2089418131 cites W1983851236 @default.
• W2089418131 cites W1985876268 @default.
• W2089418131 cites W1985887257 @default.
• W2089418131 cites W1989057019 @default.
• W2089418131 cites W1990545618 @default.
• W2089418131 cites W1995789984 @default.
• W2089418131 cites W1997469925 @default.
• W2089418131 cites W1998264051 @default.
• W2089418131 cites W2014230003 @default.
• W2089418131 cites W2014651656 @default.
• W2089418131 cites W2016693266 @default.
• W2089418131 cites W2020088099 @default.
• W2089418131 cites W2027191569 @default.
• W2089418131 cites W2032320245 @default.
• W2089418131 cites W2032480283 @default.
• W2089418131 cites W2035388701 @default.
• W2089418131 cites W2041898835 @default.
• W2089418131 cites W2047331683 @default.
• W2089418131 cites W2049251170 @default.
• W2089418131 cites W2050567744 @default.
• W2089418131 cites W2058235771 @default.
• W2089418131 cites W2062300120 @default.
• W2089418131 cites W2067949392 @default.
• W2089418131 cites W2073068828 @default.
• W2089418131 cites W2083453910 @default.
• W2089418131 cites W2088925212 @default.
• W2089418131 cites W2090207871 @default.
• W2089418131 cites W2108825582 @default.
• W2089418131 cites W2110742807 @default.
• W2089418131 cites W2116847017 @default.
• W2089418131 cites W2120784227 @default.
• W2089418131 cites W2125912753 @default.
• W2089418131 cites W2126332265 @default.
• W2089418131 cites W2135905960 @default.
• W2089418131 cites W2146588450 @default.
• W2089418131 cites W2148294261 @default.
• W2089418131 cites W2148635708 @default.
• W2089418131 cites W2155995610 @default.
• W2089418131 cites W2166191977 @default.
• W2089418131 cites W2235731464 @default.
• W2089418131 cites W2314789569 @default.
• W2089418131 cites W2398103039 @default.
• W2089418131 cites W2411721958 @default.
• W2089418131 cites W2415283668 @default.
• W2089418131 cites W2440321676 @default.
• W2089418131 cites W251109853 @default.
• W2089418131 cites W2739708591 @default.
• W2089418131 cites W3024152856 @default.
• W2089418131 cites W34840195 @default.
• W2089418131 cites W4327766605 @default.
• W2089418131 cites W89931037 @default.
• W2089418131 doi "https://doi.org/10.1083/jcb.100.4.997" @default.
• W2089418131 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2113775" @default.
• W2089418131 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2579960" @default.
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