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- W2089451886 abstract "LUTS and erectile dysfunction often coexist in men, particularly with advancing age. The recent evidence that PDE-5 inhibitors generate improvement in ED as well as LUTS, suggest that they might be of particular value in patients with both these conditions, as single agents. To date, there are no large studies designed that directly compare alpha-blockers with PDE-5 inhibitor in LUTS. The question of whether PDE-5 inhibitors are as efficacious as alpha-blockers in LUTS currently cannot be answered by these studies. The present study was conceptualized with the aim to directly compare the efficacy of a PDE-5 inhibitor (tadalafil) and an alpha-blocker (tamsulosin), in relieving LUTS in patients with BPH, and to evaluate efficacy, and safety, of tadalafil in patients with LUTS secondary to benign prostatic hyperplasia and compare it with tamsulosin." @default.
- W2089451886 created "2016-06-24" @default.
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- W2089451886 date "2010-09-01" @default.
- W2089451886 modified "2023-09-25" @default.
- W2089451886 title "UP-1.50: Tadalafil monotherapy is as efficacious as tamsulosin in patients with LUTS secondary to BPH: results of first head-on comparative, prospective, randomized study to evaluate the efficacy of tadalafil and tamsulosin, in patients with LUTS secondary to BPH" @default.
- W2089451886 doi "https://doi.org/10.1016/j.urology.2010.07.183" @default.
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