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- W2089642109 abstract "The mouse zona piercing process in piezodriven intracytoplasmic sperm injection (piezo-ICSI) is modeled and simulated with the material point method (MPM) to study the physics behind the piercing process. The MPM simulation reveals that the lateral vibration of the injection pipette plays a key role in the piercing process and disproves the claim that the axial displacement of the pipette pierces the zona. The lateral vibration of the injection pipette is further analyzed using the finite element method to investigate the role of mercury in the piercing process. It is shown that the use of mercury generally reduces the amplitude of the pipette tip and that a shorter piezopulse duration results in a smaller vibration amplitude. This implies that the effect of mercury on the piezo-ICSI procedure may lie in causing less oocyte damage due to the reduced amplitude of the pipette tip, and the development of a piezo-ICSI procedure without using mercury is possible by changing the dimensions of the injection micropipette and the piezodrill controller parameters." @default.
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- W2089642109 date "2008-08-15" @default.
- W2089642109 modified "2023-09-28" @default.
- W2089642109 title "A study of the zona piercing process in piezodriven intracytoplasmic sperm injection" @default.
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- W2089642109 doi "https://doi.org/10.1063/1.2970097" @default.
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