Matches in SemOpenAlex for { <https://semopenalex.org/work/W2089684141> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2089684141 endingPage "337" @default.
- W2089684141 startingPage "330" @default.
- W2089684141 abstract "The long-term outcome of hypersensitivity pneumonitis (HP) is variable depending upon the individual. To evaluate the mechanisms involved in the progression or regression of HP, the longitudinal changes in pulmonary function test results, bronchoalveolar lavage (BAL) cells and the subclass distribution of IgA and IgG antibodies were investigated in 14 patients with HP, including 5 cases with bird fancier's lung (BFL). The present study has shown that: (1) All patients with bird fancier's lung (BFL) demonstrated either a restrictive pattern or a reduced diffusing capacity for carbon monoxide (DLco), or both; one BFL patient showed deterioration in %VC and %DLco after avoidance of direct exposure. (2) All three patients with summer type HP who demonstrated reduced VC and DLco at the initial test improved, (3) T cells, especially CD8 cells, were predominant in the BAL fluids of the summer type HP patients, whereas either CD8 or CD4 cells were less common, but showed an increase in the BAL fluids of the BFL patients, depending upon individuals, (4) The number of CD8 cells in the summer type HP patients decreased gradually, but at slower rate than in the BFL patients; (5) Antibody activities of IgG1, G2, G3, G4, and A1 subclasses in the sera and BAL fluids were detected during the 5-year observation period; (6) IgA2 subclass was abundant in the BAL fluids of both BFL and summer type HP patients, in contrast to very minute amounts in sera; (7) The level of IgG2 antibody in the BAL fluids of the summer type HP patients was low (0.15 +/- 0.05) as compared to that in BFL (0.82 +/- 0.29); (8) The level of IgG3 antibody in the BAL fluids of summer type HP patients was lower (0.18 +/- 0.05) than in BFL (1.01 +/- 0.1); and (9) The antibody activities in most immunoglobulin subclasses fluctuated, but declined gradually in the BAL fluids, although they were well beyond the normal ranges. We were unable to predict the progression or the disappearance of hypersensitivity pneumonitis based merely upon the results of the present study." @default.
- W2089684141 created "2016-06-24" @default.
- W2089684141 creator A5016207515 @default.
- W2089684141 creator A5032709542 @default.
- W2089684141 creator A5034173750 @default.
- W2089684141 creator A5047115124 @default.
- W2089684141 creator A5056696875 @default.
- W2089684141 creator A5071366186 @default.
- W2089684141 creator A5090461473 @default.
- W2089684141 date "1994-12-01" @default.
- W2089684141 modified "2023-09-23" @default.
- W2089684141 title "Sequential Evaluation of Clinical and Immunological Findings in Hypersensitivity Pneumonitis: Serial Subclass Distribution of Antibodies" @default.
- W2089684141 doi "https://doi.org/10.1006/clin.1994.1206" @default.
- W2089684141 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7955561" @default.
- W2089684141 hasPublicationYear "1994" @default.
- W2089684141 type Work @default.
- W2089684141 sameAs 2089684141 @default.
- W2089684141 citedByCount "13" @default.
- W2089684141 countsByYear W20896841412020 @default.
- W2089684141 crossrefType "journal-article" @default.
- W2089684141 hasAuthorship W2089684141A5016207515 @default.
- W2089684141 hasAuthorship W2089684141A5032709542 @default.
- W2089684141 hasAuthorship W2089684141A5034173750 @default.
- W2089684141 hasAuthorship W2089684141A5047115124 @default.
- W2089684141 hasAuthorship W2089684141A5056696875 @default.
- W2089684141 hasAuthorship W2089684141A5071366186 @default.
- W2089684141 hasAuthorship W2089684141A5090461473 @default.
- W2089684141 hasConcept C126322002 @default.
- W2089684141 hasConcept C142724271 @default.
- W2089684141 hasConcept C147483822 @default.
- W2089684141 hasConcept C159654299 @default.
- W2089684141 hasConcept C16020263 @default.
- W2089684141 hasConcept C165637977 @default.
- W2089684141 hasConcept C167672396 @default.
- W2089684141 hasConcept C203014093 @default.
- W2089684141 hasConcept C2776194381 @default.
- W2089684141 hasConcept C2777134676 @default.
- W2089684141 hasConcept C2777714996 @default.
- W2089684141 hasConcept C2777961210 @default.
- W2089684141 hasConcept C2780648854 @default.
- W2089684141 hasConcept C3018587741 @default.
- W2089684141 hasConcept C71924100 @default.
- W2089684141 hasConcept C75603125 @default.
- W2089684141 hasConceptScore W2089684141C126322002 @default.
- W2089684141 hasConceptScore W2089684141C142724271 @default.
- W2089684141 hasConceptScore W2089684141C147483822 @default.
- W2089684141 hasConceptScore W2089684141C159654299 @default.
- W2089684141 hasConceptScore W2089684141C16020263 @default.
- W2089684141 hasConceptScore W2089684141C165637977 @default.
- W2089684141 hasConceptScore W2089684141C167672396 @default.
- W2089684141 hasConceptScore W2089684141C203014093 @default.
- W2089684141 hasConceptScore W2089684141C2776194381 @default.
- W2089684141 hasConceptScore W2089684141C2777134676 @default.
- W2089684141 hasConceptScore W2089684141C2777714996 @default.
- W2089684141 hasConceptScore W2089684141C2777961210 @default.
- W2089684141 hasConceptScore W2089684141C2780648854 @default.
- W2089684141 hasConceptScore W2089684141C3018587741 @default.
- W2089684141 hasConceptScore W2089684141C71924100 @default.
- W2089684141 hasConceptScore W2089684141C75603125 @default.
- W2089684141 hasIssue "3" @default.
- W2089684141 hasLocation W20896841411 @default.
- W2089684141 hasLocation W20896841412 @default.
- W2089684141 hasOpenAccess W2089684141 @default.
- W2089684141 hasPrimaryLocation W20896841411 @default.
- W2089684141 hasRelatedWork W1970208427 @default.
- W2089684141 hasRelatedWork W2044225151 @default.
- W2089684141 hasRelatedWork W2089684141 @default.
- W2089684141 hasRelatedWork W2147383901 @default.
- W2089684141 hasRelatedWork W2215316062 @default.
- W2089684141 hasRelatedWork W2285871974 @default.
- W2089684141 hasRelatedWork W2378515794 @default.
- W2089684141 hasRelatedWork W2776299596 @default.
- W2089684141 hasRelatedWork W2777000852 @default.
- W2089684141 hasRelatedWork W3032771747 @default.
- W2089684141 hasVolume "73" @default.
- W2089684141 isParatext "false" @default.
- W2089684141 isRetracted "false" @default.
- W2089684141 magId "2089684141" @default.
- W2089684141 workType "article" @default.