FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2089732350> ?p ?o ?g. }

• W2089732350 endingPage "257" @default.
• W2089732350 startingPage "251" @default.
• W2089732350 abstract "Ensuring domestic safety from terrorist attack is a daunting challenge because of the wide array of chemical agents that must be screened. A panel of purified fluorescent protein isoforms (FPs) was screened for the ability to detect various explosives, explosive simulants, and toxic agents. In addition to their commonly used visible excitation wavelengths, essentially all FPs can be excited by UV light at 280 nm. Ultraviolet illumination excites electrons in endogenous tryptophan (W) residues, which then relax by Förster Resonance Energy Transfer (FRET) to the chromophore of the FP, and thus the FPs emit with their typical visible spectra. Taking advantage of the fact that tryptophan excitation can be quenched by numerous agents, including nitroaromatics like TNT and nitramines like RDX, it is demonstrated that quenching of visible fluorescence from UV illumination of FPs can be used as the basis for detecting these explosives and explosive degradation products. This work provides the foundation for production of an array of genetically-modified FPs for in vitro biosensors capable of rapid, simultaneous, sensitive and selective detection of a wide range of explosive or toxic agents." @default.
• W2089732350 created "2016-06-24" @default.
• W2089732350 creator A5007039352 @default.
• W2089732350 creator A5008784184 @default.
• W2089732350 creator A5015400612 @default.
• W2089732350 creator A5020132536 @default.
• W2089732350 creator A5043121608 @default.
• W2089732350 creator A5071722857 @default.
• W2089732350 creator A5086533305 @default.
• W2089732350 date "2013-10-01" @default.
• W2089732350 modified "2023-09-25" @default.
• W2089732350 title "Fluorescent proteins as biosensors by quenching resonance energy transfer from endogenous tryptophan: Detection of nitroaromatic explosives" @default.
• W2089732350 cites W1565722563 @default.
• W2089732350 cites W1607905455 @default.
• W2089732350 cites W1965491919 @default.
• W2089732350 cites W1968918207 @default.
• W2089732350 cites W1969292478 @default.
• W2089732350 cites W1973195800 @default.
• W2089732350 cites W1974243596 @default.
• W2089732350 cites W1980301549 @default.
• W2089732350 cites W1981864850 @default.
• W2089732350 cites W1988899769 @default.
• W2089732350 cites W1991292972 @default.
• W2089732350 cites W1996052379 @default.
• W2089732350 cites W1997784010 @default.
• W2089732350 cites W2006768910 @default.
• W2089732350 cites W2010708272 @default.
• W2089732350 cites W2026493209 @default.
• W2089732350 cites W2028066672 @default.
• W2089732350 cites W2044683923 @default.
• W2089732350 cites W2050126851 @default.
• W2089732350 cites W2051638975 @default.
• W2089732350 cites W2054411504 @default.
• W2089732350 cites W2059458381 @default.
• W2089732350 cites W2066499945 @default.
• W2089732350 cites W2067647174 @default.
• W2089732350 cites W2067677265 @default.
• W2089732350 cites W2078508078 @default.
• W2089732350 cites W2081852526 @default.
• W2089732350 cites W2083414265 @default.
• W2089732350 cites W2085662845 @default.
• W2089732350 cites W2086724978 @default.
• W2089732350 cites W2096546445 @default.
• W2089732350 cites W2099015633 @default.
• W2089732350 cites W2099376237 @default.
• W2089732350 cites W2104946653 @default.
• W2089732350 cites W2116615213 @default.
• W2089732350 cites W2119367395 @default.
• W2089732350 cites W2140443576 @default.
• W2089732350 cites W2143094150 @default.
• W2089732350 cites W2146292829 @default.
• W2089732350 cites W2155974000 @default.
• W2089732350 cites W2161574340 @default.
• W2089732350 cites W2162407681 @default.
• W2089732350 cites W2165429223 @default.
• W2089732350 cites W2168399384 @default.
• W2089732350 cites W2317688512 @default.
• W2089732350 cites W2318116718 @default.
• W2089732350 cites W4241299767 @default.
• W2089732350 doi "https://doi.org/10.1016/j.bios.2013.03.076" @default.
• W2089732350 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23708748" @default.
• W2089732350 hasPublicationYear "2013" @default.
• W2089732350 type Work @default.
• W2089732350 sameAs 2089732350 @default.
• W2089732350 citedByCount "23" @default.
• W2089732350 countsByYear W20897323502013 @default.
• W2089732350 countsByYear W20897323502014 @default.
• W2089732350 countsByYear W20897323502015 @default.
• W2089732350 countsByYear W20897323502016 @default.
• W2089732350 countsByYear W20897323502018 @default.
• W2089732350 countsByYear W20897323502019 @default.
• W2089732350 countsByYear W20897323502020 @default.
• W2089732350 countsByYear W20897323502021 @default.
• W2089732350 countsByYear W20897323502023 @default.
• W2089732350 crossrefType "journal-article" @default.
• W2089732350 hasAuthorship W2089732350A5007039352 @default.
• W2089732350 hasAuthorship W2089732350A5008784184 @default.
• W2089732350 hasAuthorship W2089732350A5015400612 @default.
• W2089732350 hasAuthorship W2089732350A5020132536 @default.
• W2089732350 hasAuthorship W2089732350A5043121608 @default.
• W2089732350 hasAuthorship W2089732350A5071722857 @default.
• W2089732350 hasAuthorship W2089732350A5086533305 @default.
• W2089732350 hasConcept C120665830 @default.
• W2089732350 hasConcept C121332964 @default.
• W2089732350 hasConcept C121745418 @default.
• W2089732350 hasConcept C154238967 @default.
• W2089732350 hasConcept C160756335 @default.
• W2089732350 hasConcept C171250308 @default.
• W2089732350 hasConcept C178790620 @default.
• W2089732350 hasConcept C185592680 @default.
• W2089732350 hasConcept C192468462 @default.
• W2089732350 hasConcept C192562407 @default.
• W2089732350 hasConcept C2776706248 @default.
• W2089732350 hasConcept C515207424 @default.
• W2089732350 hasConcept C55493867 @default.
• W2089732350 hasConcept C75473681 @default.
• W2089732350 hasConcept C91881484 @default.
• W2089732350 hasConcept C96305047 @default.

• next