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• W2089734053 abstract "A neurofibromatosis type 1 (NF1) based bioassay-guided phytochemical investigation on Simarouba berteroana led to the isolation of one new canthin-6-one-9-methoxy-5-O-β-D-glucopyranoside (1), seven known canthine alkaloids (2-8), two known quassinoids (9-10) and a known neo-lignan (11). The structures of all compounds were established by HRMS, 1D- and 2D-NMR analysis and comparison with previously reported data. Most of the compounds inhibited the proliferation of an Nf1- and p53-deficient mouse glioma cell line at non-cytotoxic concentrations." @default.
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• W2089734053 date "2014-02-01" @default.
• W2089734053 modified "2023-09-23" @default.
• W2089734053 title "Compounds from Simarouba berteroana which inhibit proliferation of NF1-defective cancer cells" @default.
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• W2089734053 doi "https://doi.org/10.1016/j.phytol.2013.09.007" @default.
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