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- W2089746688 abstract "SIROLIMUS COMMONLY is administered in calcineurin-inhibitor–sparing regimens to avoid nephrotoxicity in transplantation. 1 Halloran P.F. Immunosuppressive drugs for kidney transplantation. N Engl J Med. 2004; 351: 2715-2729 Crossref PubMed Scopus (1154) Google Scholar However, there are reports of acute renal failure, 2 Lawsin L. Light J.A. Severe acute renal failure after exposure to sirolimus-tacrolimus in two living donor kidney recipients. Transplantation. 2003; 75: 157-160 Crossref PubMed Scopus (39) Google Scholar thrombotic microangiopathy, 3 Crew R.J. Radhakrishnan J. Cohen D.J. et al. De novo thrombotic microangiopathy following treatment with sirolimus Report of two cases. Nephrol Dial Transplant. 2005; 20: 203-209 Crossref PubMed Scopus (43) Google Scholar and glomerulonephritis with worsening of proteinuria associated with sirolimus therapy. 4 Fervenza F.C. Fitzpatrick P.M. Mertz J. et al. Acute rapamycin nephrotoxicity in native kidneys of patients with chronic glomerulopathies. Nephrol Dial Transplant. 2004; 19: 1288-1292 Crossref PubMed Scopus (102) Google Scholar , 5 Dittritch E. Schmaldienst S. Soleiman A. Horl W.H. Pohanka E. Rapamycin-associated post-transplantation glomerulonephritis and its remission after reintroduction of calcineurin-inhibitor therapy. Transpl Int. 2004; 17: 215-220 Crossref PubMed Scopus (127) Google Scholar , 6 Jim B. Doyle A. Bloom R.D. Rapamycin is associated with worsening proteinuria in transplant patients with renal injury A report of four cases. J Am Soc Nephrol. 2003; 14 (abstr SU-FC297): 65A Crossref Google Scholar , 7 Hadaya K. Wissing M. Emine B. Daniel A. Conversion to sirolimus after renal transplantation High failure rate due to nephrotic proteinuria and other adverse events. J Am Soc Nephrol. 2003; 14 (abstr F-PO567): 185A Google Scholar We report a case of acute renal failure and increasing proteinuria in a liver transplant recipient that occurred 2 months after initiation of sirolimus therapy." @default.
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- W2089746688 date "2006-04-01" @default.
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- W2089746688 title "Acute Renal Failure in a Liver Transplant Patient After Treatment With Sirolimus" @default.
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- W2089746688 doi "https://doi.org/10.1053/j.ajkd.2005.11.034" @default.
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