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• W2089762154 abstract "The original immunocompetence handicap hypothesis (ICHH) suggested that testosterone has a handicapping effect in males by both promoting the development of sexual signals and suppressing immune function. A modified version, the stress-linked ICHH, has recently proposed that testosterone is immunosuppressive indirectly by increasing production of corticosterone. To test both the original and stress-mediated versions of the ICHH, we implanted male zebra finches taken from lines selected for divergent maximum stress-induced levels of corticosterone (high, low and control) with either empty or testosterone-filled implants. Their humoral and cell-mediated immune responses were then assessed by challenge with diphtheria:tetanus vaccine and phytohemagglutinin respectively. We found no effect of the hormone manipulations on either PHA or tetanus antibody responses, but found a significant interaction between titers of both testosterone and corticosterone on diphtheria secondary antibody response; antibody response was greatest in individuals with high levels of both hormones. There was also a significant interactive effect between testosterone treatment group and corticosterone titer on body mass; the body mass of males in the elevated testosterone treatment group decreased with increasing corticosterone titer. These results suggest that, contrary to the assumption of the stress-mediated version of the ICHH, high plasma levels of corticosterone are not immunosuppressive, but are in fact immuno-enhancing in the presence of high levels of plasma testosterone. Equally, the central assumption of the ICHH that testosterone is obligately immunosuppressive is also not supported. The same individuals with the highest levels of both hormones and consequently the most robust antibody response also possessed the lowest body mass." @default.
• W2089762154 created "2016-06-24" @default.
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• W2089762154 date "2007-01-01" @default.
• W2089762154 modified "2023-09-27" @default.
• W2089762154 title "Effects of testosterone and corticosterone on immunocompetence in the zebra finch" @default.
• W2089762154 cites W1840277495 @default.
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• W2089762154 cites W1974757741 @default.
• W2089762154 cites W1976642916 @default.
• W2089762154 cites W1978084352 @default.
• W2089762154 cites W1979443266 @default.
• W2089762154 cites W1980569454 @default.
• W2089762154 cites W1984784105 @default.
• W2089762154 cites W1992690084 @default.
• W2089762154 cites W1996539684 @default.
• W2089762154 cites W2000022077 @default.
• W2089762154 cites W2001834413 @default.
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• W2089762154 cites W2030145613 @default.
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• W2089762154 cites W2051558840 @default.
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• W2089762154 cites W2052735134 @default.
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• W2089762154 doi "https://doi.org/10.1016/j.yhbeh.2006.09.004" @default.
• W2089762154 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17049519" @default.
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