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- W2089826995 abstract "Blom et al. confirmed the risk for upper extremity deep vein thrombosis (DVT) in patients with malignant disease and central venous catheters [1-3]. The complexity of cancer disease management may influence the validity of the data. Chemotherapy alone may lead to hypercoagulability [4] and upper extremity DVT [5]. The type of the central venous catheter influences the rate of thrombotic complication [6]. Infections of central venous catheters increase the risk of catheter-related thrombosis in patients with malignancy [7]. Prophylaxis of venous thromboembolism with heparin, low-molecular-weight heparin or low-dose warfarin may reduce the incidence of catheter-related thrombosis, which is however, not yet a standard procedure, as discussed by the authors [8]. These risk factors and the prophylactic measures have not been documented in the study and may substantially influence the reported data. Thus, the data does not support the conclusion that central venous line alone is, a very strong risk factor for arm vein thrombosis. The present data only indicate an increased risk for upper extremity DVT by the combination of central venous line and chemotherapy. Additional information on the type of central venous catheter, concomitant infection, the type of the central venous line and the use of anticoagulants in or out of hospital would define precisely the risk factors for upper extremity DVT and the outcome of the patients." @default.
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- W2089826995 date "2006-04-01" @default.
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- W2089826995 title "Old and new risk factors for upper extremity deep venous thrombosis – a rebuttal" @default.
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- W2089826995 doi "https://doi.org/10.1111/j.1538-7836.2006.01836.x" @default.
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