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- W2089866549 abstract "The intralesional expression of cytokines (interleukin [IL]–4, IL-13, IL-10, and interferon-γ) was analyzed in 65 patients with localized cutaneous leishmaniasis due to Leishmania guyanensis before specific treatment with pentamidine isethionate. The local expression of IL-10 was significantly higher in patients who responded poorly to treatment than in patients whose lesions were regressing. When an IL-10 level >10 (ratio of the concentration of IL-10 [pg/μL] to that of β-actin [pg/μL]) was used as an indicator of treatment failure, the sensitivity of this test was 78.6, and the specificity was 72.5. Thus, high intralesional expression of IL-10 might predict a poor response to conventional treatment" @default.
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- W2089866549 date "2001-12-15" @default.
- W2089866549 modified "2023-10-14" @default.
- W2089866549 title "High Intralesional Interleukin‐10 Messenger RNA Expression in Localized Cutaneous Leishmaniasis Is Associated with Unresponsiveness to Treatment" @default.
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- W2089866549 doi "https://doi.org/10.1086/324665" @default.
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