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- W2089872281 abstract "The sweetness values of saccharin, acesulfame-K and cyclatmate have been rationalised on the basis of molecular models of their multiple interactions with our α-helical protein receptor, in which the hydrophobic attractions within a crevice of the helix are critical for both sweetness and intensity. The study was carried out by modelling of the host-guest molecules, joined by hydrogen bonds and assessment of their non-bonded hydrophobic interactions, as determined by three-dimensional computer graphics. Both enhancement and loss of sweetness in these disulphoxide derivatives were then interpreted on this basic premise." @default.
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- W2089872281 date "1998-11-01" @default.
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- W2089872281 title "Molecular mechanisms of sweet taste 8: saccharin, acesulfame-K, cyclamate and their derivatives" @default.
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- W2089872281 doi "https://doi.org/10.1016/s0308-8146(97)00241-0" @default.
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