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- W2089912419 abstract "Following implantation of biomaterial patches into the gastrointestinal tract, we analyzed the host's response towards the foreign material. Asymmetric patches of polydioxanone covered Vicryl or poly-3-hydroxybutyrate were sutured onto the rat stomach. Tissue samples were generated at distinct time intervals after surgery, and RNA profiles were compared by Differential Display. RT-PCR analysis of gene candidates that seemed differentially expressed showed that vitamin D binding protein mRNA was induced in stomach tissue after implantation of the biomaterial patches. In parallel, the amount of C-reactive protein mRNA was found to be increased transiently as well. Implants induce a tissue response that is specific for a given material." @default.
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- W2089912419 date "2002-04-18" @default.
- W2089912419 modified "2023-10-17" @default.
- W2089912419 title "Biomaterial implants induce the inflammation marker CRP at the site of implantation" @default.
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- W2089912419 doi "https://doi.org/10.1002/jbm.10155" @default.
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