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- W2089925344 abstract "In short-term incubations of fat cells isolated from human adipose tissue, noradrenaline (0.2-2x10--5 M), a mixed alpha and beta-adrenergic agonist, stimulated only slightly cyclic AMP accumulation. In the presence of the alpha-adrenergic blocking agent phentolamine (0.05-5mug/ml), noradrenaline markedly augmented the amount of labelled cyclic nucleotide. The stiumlatory effect of noradrenaline and noradrenaline plus phentolamine was abolished by propranolol (0.1-10 mug/ml). Theophylline (10--4-10--3 M) slightly increased the (3-H) cyclic AMP levels per se and magnified the stiumulatory action of other agents, but did not mimic the potentiating effect of phentolamine on noradrenaline action." @default.
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- W2089925344 date "1975-01-12" @default.
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- W2089925344 title "DYNAMICS OF α-ADRENERGIC INHIBITION OF THE ADENYL CYCLASE-CYCLIC AMP SYSTEM IN HUMAN ADIPOSE TISSUE" @default.
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- W2089925344 doi "https://doi.org/10.1111/j.0954-6820.1975.tb04918.x" @default.
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