FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2089925865> ?p ?o ?g. }

• W2089925865 endingPage "209" @default.
• W2089925865 startingPage "205" @default.
• W2089925865 abstract "Based on its unique pharmacological profile, buprenorphine may produce less impairment in psychomotor and cognitive performance than methadone. However, the few studies that have investigated the performance effects of buprenorphine in opioid-abusing volunteers examined effects of single acute doses rather than effects of repeated dosing and included a very limited range of measures. The present inpatient study evaluated dose-related effects of repeated administration of the buprenorphine/naloxone combination product (8/2, 16/4, 32/8 mg, sublingual tablets) in eight opioid-dependent volunteers on performance of a broad range of tasks, following a period of 7-10 days of dosing at each level, in a double-blind, within-subject, crossover design. The testing battery included measures of psychomotor speed, time perception, conceptual flexibility, focused attention, working memory, long-term/episodic memory, and metamemory. Supporting the hypothesis of limited impairment with buprenorphine, results revealed minimal impairment in performance as buprenorphine/naloxone dose was increased four-fold. The only significant effect of dose was an impairment in episodic/long-term memory (recognition memory) performance at the highest dose (32/8 mg) relative to the two lower doses. Future studies incorporating larger sample sizes and non-drug controls, as well as directly comparing buprenorphine to methadone and LAAM are needed to further test the hypothesis of limited impairment with buprenorphine." @default.
• W2089925865 created "2016-06-24" @default.
• W2089925865 creator A5017911936 @default.
• W2089925865 creator A5021954661 @default.
• W2089925865 creator A5065626177 @default.
• W2089925865 date "2004-05-01" @default.
• W2089925865 modified "2023-10-01" @default.
• W2089925865 title "A dose–effect study of repeated administration of buprenorphine/naloxone on performance in opioid-dependent volunteers" @default.
• W2089925865 cites W1965602674 @default.
• W2089925865 cites W1977681341 @default.
• W2089925865 cites W1978487890 @default.
• W2089925865 cites W1980330516 @default.
• W2089925865 cites W1991765221 @default.
• W2089925865 cites W1992389336 @default.
• W2089925865 cites W2008032124 @default.
• W2089925865 cites W2011860072 @default.
• W2089925865 cites W2020031422 @default.
• W2089925865 cites W2026733344 @default.
• W2089925865 cites W2034046163 @default.
• W2089925865 cites W2043965534 @default.
• W2089925865 cites W2055760308 @default.
• W2089925865 cites W2068839310 @default.
• W2089925865 cites W2071893208 @default.
• W2089925865 cites W2077440339 @default.
• W2089925865 cites W2086512215 @default.
• W2089925865 cites W2123299892 @default.
• W2089925865 cites W2147186992 @default.
• W2089925865 cites W2152947180 @default.
• W2089925865 cites W2153004096 @default.
• W2089925865 cites W2163106907 @default.
• W2089925865 cites W2414621056 @default.
• W2089925865 cites W4244152110 @default.
• W2089925865 cites W4292692520 @default.
• W2089925865 doi "https://doi.org/10.1016/j.drugalcdep.2003.12.008" @default.
• W2089925865 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15099664" @default.
• W2089925865 hasPublicationYear "2004" @default.
• W2089925865 type Work @default.
• W2089925865 sameAs 2089925865 @default.
• W2089925865 citedByCount "36" @default.
• W2089925865 countsByYear W20899258652012 @default.
• W2089925865 countsByYear W20899258652013 @default.
• W2089925865 countsByYear W20899258652015 @default.
• W2089925865 countsByYear W20899258652016 @default.
• W2089925865 countsByYear W20899258652018 @default.
• W2089925865 countsByYear W20899258652019 @default.
• W2089925865 countsByYear W20899258652020 @default.
• W2089925865 countsByYear W20899258652021 @default.
• W2089925865 countsByYear W20899258652022 @default.
• W2089925865 countsByYear W20899258652023 @default.
• W2089925865 crossrefType "journal-article" @default.
• W2089925865 hasAuthorship W2089925865A5017911936 @default.
• W2089925865 hasAuthorship W2089925865A5021954661 @default.
• W2089925865 hasAuthorship W2089925865A5065626177 @default.
• W2089925865 hasConcept C102959455 @default.
• W2089925865 hasConcept C105795698 @default.
• W2089925865 hasConcept C118552586 @default.
• W2089925865 hasConcept C126322002 @default.
• W2089925865 hasConcept C142724271 @default.
• W2089925865 hasConcept C15744967 @default.
• W2089925865 hasConcept C164953862 @default.
• W2089925865 hasConcept C169900460 @default.
• W2089925865 hasConcept C170493617 @default.
• W2089925865 hasConcept C204787440 @default.
• W2089925865 hasConcept C27081682 @default.
• W2089925865 hasConcept C2777288759 @default.
• W2089925865 hasConcept C2778750930 @default.
• W2089925865 hasConcept C2778767360 @default.
• W2089925865 hasConcept C2778949969 @default.
• W2089925865 hasConcept C2781063702 @default.
• W2089925865 hasConcept C33923547 @default.
• W2089925865 hasConcept C42219234 @default.
• W2089925865 hasConcept C71924100 @default.
• W2089925865 hasConcept C87813604 @default.
• W2089925865 hasConcept C98274493 @default.
• W2089925865 hasConceptScore W2089925865C102959455 @default.
• W2089925865 hasConceptScore W2089925865C105795698 @default.
• W2089925865 hasConceptScore W2089925865C118552586 @default.
• W2089925865 hasConceptScore W2089925865C126322002 @default.
• W2089925865 hasConceptScore W2089925865C142724271 @default.
• W2089925865 hasConceptScore W2089925865C15744967 @default.
• W2089925865 hasConceptScore W2089925865C164953862 @default.
• W2089925865 hasConceptScore W2089925865C169900460 @default.
• W2089925865 hasConceptScore W2089925865C170493617 @default.
• W2089925865 hasConceptScore W2089925865C204787440 @default.
• W2089925865 hasConceptScore W2089925865C27081682 @default.
• W2089925865 hasConceptScore W2089925865C2777288759 @default.
• W2089925865 hasConceptScore W2089925865C2778750930 @default.
• W2089925865 hasConceptScore W2089925865C2778767360 @default.
• W2089925865 hasConceptScore W2089925865C2778949969 @default.
• W2089925865 hasConceptScore W2089925865C2781063702 @default.
• W2089925865 hasConceptScore W2089925865C33923547 @default.
• W2089925865 hasConceptScore W2089925865C42219234 @default.
• W2089925865 hasConceptScore W2089925865C71924100 @default.
• W2089925865 hasConceptScore W2089925865C87813604 @default.
• W2089925865 hasConceptScore W2089925865C98274493 @default.
• W2089925865 hasIssue "2" @default.
• W2089925865 hasLocation W20899258651 @default.
• W2089925865 hasLocation W20899258652 @default.

• next