FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2089968500> ?p ?o ?g. }

• W2089968500 endingPage "1139" @default.
• W2089968500 startingPage "1134" @default.
• W2089968500 abstract "The immunological characteristics of SARS-CoV spike protein were investigated by administering mice with plasmids encoding various S gene fragments. We showed that the secreting forms of S1, S2 subunits and the N-terminus of S1 subunit (residues 18-495) were capable of eliciting SARS-CoV specific antibodies and the region immediate to N-terminus of matured S1 protein contained an important immunogenic determinant for elicitation of SARS-CoV specific antibodies. In addition, mice immunized with plasmids encoding S1 fragment developed a Th1-mediated antibody isotype switching. Another interesting finding was that mouse antibodies elicited separately by plasmids encoding S1 and S2 subunits cooperatively neutralized SARS-CoV but neither the S1 nor S2 specific antibodies did, suggesting the possible role of both S1 and S2 subunits in host cell docking and entry. These results provide insights into understanding the immunological characteristics of spike protein and the development of subunit vaccines against SARS-CoV." @default.
• W2089968500 created "2016-06-24" @default.
• W2089968500 creator A5006065098 @default.
• W2089968500 creator A5006135413 @default.
• W2089968500 creator A5019767879 @default.
• W2089968500 creator A5033878772 @default.
• W2089968500 creator A5038322039 @default.
• W2089968500 creator A5039131672 @default.
• W2089968500 creator A5056638183 @default.
• W2089968500 creator A5086755950 @default.
• W2089968500 date "2004-03-01" @default.
• W2089968500 modified "2023-10-16" @default.
• W2089968500 title "Characterization of humoral responses in mice immunized with plasmid DNAs encoding SARS-CoV spike gene fragments" @default.
• W2089968500 cites W1966238900 @default.
• W2089968500 cites W1980278889 @default.
• W2089968500 cites W1987696716 @default.
• W2089968500 cites W1994670656 @default.
• W2089968500 cites W1998663114 @default.
• W2089968500 cites W1999639343 @default.
• W2089968500 cites W2000209824 @default.
• W2089968500 cites W2006785079 @default.
• W2089968500 cites W2009550160 @default.
• W2089968500 cites W2013037536 @default.
• W2089968500 cites W2019425552 @default.
• W2089968500 cites W2022372613 @default.
• W2089968500 cites W2025170735 @default.
• W2089968500 cites W2070572002 @default.
• W2089968500 cites W2077489286 @default.
• W2089968500 cites W2096733579 @default.
• W2089968500 cites W2097188280 @default.
• W2089968500 cites W2113469729 @default.
• W2089968500 cites W2118612771 @default.
• W2089968500 cites W2123540668 @default.
• W2089968500 cites W2128719418 @default.
• W2089968500 cites W2137976135 @default.
• W2089968500 cites W2141877163 @default.
• W2089968500 cites W2146476111 @default.
• W2089968500 cites W2161315652 @default.
• W2089968500 cites W2166185221 @default.
• W2089968500 cites W2200783653 @default.
• W2089968500 cites W2361778066 @default.
• W2089968500 cites W329076267 @default.
• W2089968500 cites W4291206361 @default.
• W2089968500 doi "https://doi.org/10.1016/j.bbrc.2004.01.166" @default.
• W2089968500 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7111006" @default.
• W2089968500 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14985131" @default.
• W2089968500 hasPublicationYear "2004" @default.
• W2089968500 type Work @default.
• W2089968500 sameAs 2089968500 @default.
• W2089968500 citedByCount "57" @default.
• W2089968500 countsByYear W20899685002013 @default.
• W2089968500 countsByYear W20899685002014 @default.
• W2089968500 countsByYear W20899685002019 @default.
• W2089968500 countsByYear W20899685002020 @default.
• W2089968500 countsByYear W20899685002021 @default.
• W2089968500 countsByYear W20899685002022 @default.
• W2089968500 crossrefType "journal-article" @default.
• W2089968500 hasAuthorship W2089968500A5006065098 @default.
• W2089968500 hasAuthorship W2089968500A5006135413 @default.
• W2089968500 hasAuthorship W2089968500A5019767879 @default.
• W2089968500 hasAuthorship W2089968500A5033878772 @default.
• W2089968500 hasAuthorship W2089968500A5038322039 @default.
• W2089968500 hasAuthorship W2089968500A5039131672 @default.
• W2089968500 hasAuthorship W2089968500A5056638183 @default.
• W2089968500 hasAuthorship W2089968500A5086755950 @default.
• W2089968500 hasBestOaLocation W20899685001 @default.
• W2089968500 hasConcept C104292427 @default.
• W2089968500 hasConcept C104317684 @default.
• W2089968500 hasConcept C153911025 @default.
• W2089968500 hasConcept C159047783 @default.
• W2089968500 hasConcept C159654299 @default.
• W2089968500 hasConcept C22744801 @default.
• W2089968500 hasConcept C2777991845 @default.
• W2089968500 hasConcept C542903549 @default.
• W2089968500 hasConcept C54355233 @default.
• W2089968500 hasConcept C86803240 @default.
• W2089968500 hasConceptScore W2089968500C104292427 @default.
• W2089968500 hasConceptScore W2089968500C104317684 @default.
• W2089968500 hasConceptScore W2089968500C153911025 @default.
• W2089968500 hasConceptScore W2089968500C159047783 @default.
• W2089968500 hasConceptScore W2089968500C159654299 @default.
• W2089968500 hasConceptScore W2089968500C22744801 @default.
• W2089968500 hasConceptScore W2089968500C2777991845 @default.
• W2089968500 hasConceptScore W2089968500C542903549 @default.
• W2089968500 hasConceptScore W2089968500C54355233 @default.
• W2089968500 hasConceptScore W2089968500C86803240 @default.
• W2089968500 hasIssue "4" @default.
• W2089968500 hasLocation W20899685001 @default.
• W2089968500 hasLocation W20899685002 @default.
• W2089968500 hasLocation W20899685003 @default.
• W2089968500 hasLocation W20899685004 @default.
• W2089968500 hasOpenAccess W2089968500 @default.
• W2089968500 hasPrimaryLocation W20899685001 @default.
• W2089968500 hasRelatedWork W1544125995 @default.
• W2089968500 hasRelatedWork W2009966535 @default.
• W2089968500 hasRelatedWork W2019988726 @default.
• W2089968500 hasRelatedWork W2084785317 @default.
• W2089968500 hasRelatedWork W2088063203 @default.

• next