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- W2089999056 abstract "Helicobacter pylori virulence factor CagA is injected into gastric epithelial cells and undergoes tyrosine phosphorylation. Similar to mammalian Gab protein, tyrosine-phosphorylated CagA recruits and activates SHP-2 phosphatase at the plasma membrane, thereby inducing a growth factor-like effect. CagA-SHP-2 interaction may play an important role in bacterial pathogenesis, leading to gastric carcinoma." @default.
- W2089999056 created "2016-06-24" @default.
- W2089999056 creator A5061468745 @default.
- W2089999056 date "2003-02-01" @default.
- W2089999056 modified "2023-10-16" @default.
- W2089999056 title "Helicobacter pylori CagA—a potential bacterial oncoprotein that functionally mimics the mammalian Gab family of adaptor proteins" @default.
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- W2089999056 doi "https://doi.org/10.1016/s1286-4579(02)00085-0" @default.
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