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- W2090029357 abstract "Abstract In 20 obstetrically normal 1st trimester pregnant volunteers abortion had been induced successfully in 19, by Prostaglandin-Impact (PGI) technique (1). A total average dose of 12.3±0.9 mg PG F2α, delivered into the extraovular (E.O.) space, reduced the plasma P levels from an initial value of 29.4±2.5 ng/ml to 12.8±1.6 ng/ml (P Of the 20 gravidas, 10 only received PGI (Control Group), while the remaining 10 were exposed to uterine stretch, in addition to PGI (Experimental Group). Stretch had been accomplished by a “stretch balloon” filled with 200 ml saline. Comparing the Control and Experimental Groups revealed that stretch shortens the IAT and improves the AbS. This effect is very probably achieved through a stretch induced increase in the endogenous PG-synthesis of the uterus (1). This preliminary finding exposes the possibility, that pregnancy termination can be promoted by an increased involvement of endogenous PGs in the activation of the myometrium, provoked through stretch. The validity of this premise is under current examination." @default.
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- W2090029357 date "1974-04-01" @default.
- W2090029357 modified "2023-09-27" @default.
- W2090029357 title "The effect of uterine stretch on first trimester abortions induced by extraovular prostaglandin impact" @default.
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- W2090029357 doi "https://doi.org/10.1016/s0090-6980(74)80041-9" @default.
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