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• W2090126018 endingPage "1887" @default.
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• W2090126018 abstract "Proinflammatory cytokines (IL-6, IL-1beta, TNF-alpha) released during liver transplantation may affect hemodynamic stability. The aim of the present study was to analyze the association between IL-6, TNF-alpha, and IL-1beta and systemic vascular resistance during the phases of liver transplantation.The proinflammatory cytokines IL-6, IL-1beta, and TNF-alpha were analyzed in the blood of 20 consecutive patients who underwent transplantation. Blood samples were drawn from the pulmonary artery at serial times during surgery. Hemodynamic parameters were determined using a cardiac output monitor. Correlations between parameters were analyzed using the Spearman's rho and Kendall's tau-b methods.Both in the vena cava and the pulmonary artery, significant association was observed between basal values of IL-6 during hepatectomy and systemic vascular resistance during the phases of liver transplantation: hepatectomy phase (r=.76, P=.02), anhepatic phase (r=.78, P=.03) and reperfusion phase (r=.87, P=.005).Basal values of IL-6 may be considered a prognostic factor for hemodynamic performance during the phases of liver transplantation." @default.
• W2090126018 created "2016-06-24" @default.
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• W2090126018 date "2003-08-01" @default.
• W2090126018 modified "2023-09-26" @default.
• W2090126018 title "Effect of proinflammatory cytokines (IL-6, TNF-α, IL-1β) on hemodynamic performance during orthotopic liver transplantation" @default.
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• W2090126018 doi "https://doi.org/10.1016/s0041-1345(03)00603-1" @default.
• W2090126018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12962834" @default.
• W2090126018 hasPublicationYear "2003" @default.
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