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- W2090145570 abstract "Objective: To assess the diagnostic accuracy of sonohysterography (SHG) and endometrial sampling during SHG (SHGes) compared to traditional hysteroscopy and biopsy.Design: Prospective pilot study.Materials/Methods: One hundred fifteen consecutive patients referred for abnormal uterine bleeding with inhomogeneous thickened endometrium at transvaginal sonography (TVS), and absence of focal endometrial lesions at SHG, were recruited for this study. SHG was performed with a 4.7 mm intrauterine catheter. In all patients an endometrial biopsy was performed by a 20ml syringe vacuum aspiration at the end of SHG (SHGes). Procedure-related pain was assessed by a visual analogue scale. In all patients hysteroscopy (HYS) and hysteroscopic guided biopsy was performed.Results: Median age was 48 years (interquartile range 38–54). At SHG and SHGes, no/mild, moderate, and severe pain was reported by 65%, 28% and 7% of patients, respectively. Endometrial sampling was inadequate in 11% of cases. Diagnostic accuracy of sonohysterography with endometrial sampling compared to the results of hysteroscopic guided biopsy is shown in table. TableDiagnostic accuracy of sonohysterography with endometrial sampling.Sensitivity (%)Specificity (%)Positive predictive value (%)Negative predictive value (%)Simple hyperplasia (# 77)97919297Carcinoma (# 16)94999499 Open table in a new tab Conclusions: Sonohysterography with endometrial sampling was a well tolerated, cost-effective and accurate procedure to investigate patients with sonographic inhomogeneous thickened endometrium, as adequate as hysteroscopy with endometrial biopsy.Supported by: None. Objective: To assess the diagnostic accuracy of sonohysterography (SHG) and endometrial sampling during SHG (SHGes) compared to traditional hysteroscopy and biopsy. Design: Prospective pilot study. Materials/Methods: One hundred fifteen consecutive patients referred for abnormal uterine bleeding with inhomogeneous thickened endometrium at transvaginal sonography (TVS), and absence of focal endometrial lesions at SHG, were recruited for this study. SHG was performed with a 4.7 mm intrauterine catheter. In all patients an endometrial biopsy was performed by a 20ml syringe vacuum aspiration at the end of SHG (SHGes). Procedure-related pain was assessed by a visual analogue scale. In all patients hysteroscopy (HYS) and hysteroscopic guided biopsy was performed. Results: Median age was 48 years (interquartile range 38–54). At SHG and SHGes, no/mild, moderate, and severe pain was reported by 65%, 28% and 7% of patients, respectively. Endometrial sampling was inadequate in 11% of cases. Diagnostic accuracy of sonohysterography with endometrial sampling compared to the results of hysteroscopic guided biopsy is shown in table. Conclusions: Sonohysterography with endometrial sampling was a well tolerated, cost-effective and accurate procedure to investigate patients with sonographic inhomogeneous thickened endometrium, as adequate as hysteroscopy with endometrial biopsy. Supported by: None." @default.
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- W2090145570 date "2002-09-01" @default.
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- W2090145570 title "Endometrial sampling during sonohysterography (SHGes) in the management of abnormal uterine bleeding" @default.
- W2090145570 doi "https://doi.org/10.1016/s0015-0282(02)03618-x" @default.
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