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- W2090147783 abstract "The c-erbB-2 proto-oncogene encodes a growth factor receptor which is over-expressed in a variety of human adenocarcinomas. Recent reports suggest that it may be of value in arriving at prognosis in breast and ovarian cancer. In this study, c-erbB-2 expression was investigated in 93 routinely processed cases of gastric carcinoma, using an immunohisto-chemical technique. c-erbB-2 membrane immunoreactivity was observed in 11% (10/93) of tumours, all of whkh were of the well differentiated intestinal type (p < 0.01). Overall, patients with tumours expressing this proto-oncogene had a significantly improved prognosis (p < 0.05). Within the group of intestinal-type tumours, those that were c-erbB-2-positive formed a distinct sub-population which had a better prognosis (p < 0.02), suggesting possible differences in aetiology." @default.
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- W2090147783 date "1991-07-09" @default.
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- W2090147783 title "c-erbB-2 proto-oncogene expression and its relationship to survival in gastric carcinoma: An immunohistochemical study on archival material" @default.
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- W2090147783 doi "https://doi.org/10.1002/ijc.2910480506" @default.
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