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- W2090150700 abstract "Chronic myelogenous leukemia (CML) can usually be cured by bone marrow transplantation from matched donors. Donor T-cell activity from the graft is critical to maintaining remission. Myeloablation may not be necessary for cure. Non-myeloablative but immunosuppressive preparative regimens allow donor engraftment with less toxicity. Early combination therapy with interferon-alfa and cytarabine was the preferred option for patients who could not undergo bone marrow transplantation. Now, the advent of imatinib mesylate, a specific inhibitor of BCR/ABL tyrosine kinase, promises to change existing treatment paradigms" @default.
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- W2090150700 date "2001-11-01" @default.
- W2090150700 modified "2023-09-25" @default.
- W2090150700 title "Chronic myelogenous leukemia: the news you have and haven't heard." @default.
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- W2090150700 doi "https://doi.org/10.3949/ccjm.68.11.913" @default.
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