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• W2090158082 abstract "The administration of p-chlorophenylalanine (PCPA), an inhibitor of serotonin (5-HT) biosynthesis, at the end of a 48 h sleep deprivation does not impair the subsequent rebound of deep slow wave sleep (SWS2) and paradoxical sleep (PS). On the contrary, the administration of PCPA during a 48 h sleep deprivation is followed by a great decrease of light slow wave sleep (SWS1) and by total disappearance of SWS2 while some rebound of PS still occurs in narcoleptic-like attacks. These experiments provide evidence that sleep inducing materials are accumulated during sleep deprivation. Serotonergic processes appear to be involved in the regulatory mechanisms of the biosynthesis and the accumulation of SWS2 and PS factors." @default.
• W2090158082 created "2016-06-24" @default.
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• W2090158082 date "1983-05-01" @default.
• W2090158082 modified "2023-09-25" @default.
• W2090158082 title "Serotonergic mechanisms and sleep rebound" @default.
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• W2090158082 doi "https://doi.org/10.1016/0006-8993(83)90393-1" @default.
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