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• W2090161053 abstract "Bacterial superantigens such as staphylococcal enterotoxin B (SEB) cause in vivo a profound and long-lasting state of unresponsiveness in ligand-reactive T cells. To test whether presentation of SEB by small resting B cells to ligand-reactive T cells is essential for the induction of T cell unresponsiveness, we analyzed the effect of SEB in B cell-deficient mice. We observed T cell deletion and T cell unresponsiveness in both B cell-deficient mice and control mice. We conclude that presentation of SEB by resting B cells is not a prerequisite for the induction of T cell unresponsiveness in vivo." @default.
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• W2090161053 date "1995-11-01" @default.
• W2090161053 modified "2023-09-26" @default.
• W2090161053 title "Bacterial superantigens induce T cell unresponsiveness in B cell-deficient mice" @default.
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• W2090161053 doi "https://doi.org/10.1002/eji.1830251130" @default.
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