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- W2090161808 abstract "Three theoretical aspects of single-channel current analysis are presented: (1) A stochastic theory of a stationary multichannel system is developed, based on the so-called basic theorem. The dwell-time distribution of every type of period between successive open or shut transitions and other stochastic properties is obtained. Analysis and computer-simulation errors are estimated. (2) Two properties satisfied by channels in equilibrium are shown: (i) Any of the probability density functions of dwell times are expressed by the sum of decaying exponentials with positive coefficients. (ii) The state transition time course from state I to J is proportional to that from J to I. (3) A steady/equilibrium approximation is presented that simplifies a complex channel model containing both short-lifetime and long-lifetime states and gives a reduced model containing only long-lifetime states. >" @default.
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- W2090161808 date "1988-01-01" @default.
- W2090161808 modified "2023-09-25" @default.
- W2090161808 title "Theoretical approach to ion channel dynamics" @default.
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- W2090161808 doi "https://doi.org/10.1109/iembs.1988.94972" @default.
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