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- W2090171454 endingPage "573" @default.
- W2090171454 startingPage "561" @default.
- W2090171454 abstract "Inorganic nanoparticles (NPs) including semiconductor quantum dots (QDs), iron oxide NPs and gold NPs have been developed as contrast agents for diagnostics by molecular imaging. Compared with traditional contrast agents, NPs offer several advantages: their optical and magnetic properties can be tailored by engineering the composition, structure, size and shape; their surfaces can be modified with ligands to target specific biomarkers of disease; the contrast enhancement provided can be equivalent to millions of molecular counterparts; and they can be integrated with a combination of different functions for multimodal imaging. Here, we review recent advances in the development of contrast agents based on inorganic NPs for molecular imaging, and also touch on contrast enhancement, surface modification, tissue targeting, clearance and toxicity. As research efforts intensify, contrast agents based on inorganic NPs that are highly sensitive, target-specific and safe to use are expected to enter clinical applications in the near future." @default.
- W2090171454 created "2016-06-24" @default.
- W2090171454 creator A5020966645 @default.
- W2090171454 creator A5041556229 @default.
- W2090171454 creator A5045109911 @default.
- W2090171454 creator A5052638367 @default.
- W2090171454 creator A5066557860 @default.
- W2090171454 date "2010-12-01" @default.
- W2090171454 modified "2023-10-16" @default.
- W2090171454 title "Inorganic nanoparticle-based contrast agents for molecular imaging" @default.
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