FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090172011> ?p ?o ?g. }

• W2090172011 endingPage "2089" @default.
• W2090172011 startingPage "2083" @default.
• W2090172011 abstract "The aim of this study was to compare the concordance between immunohistochemical (IHC) and biochemical (RIA) methods for determining hormone receptor status in patients with endometrial carcinoma and to determine whether IHC expression of estrogen and progesterone receptors (ER and PR) has prognostic significance.Paraffin blocks were obtained from patients diagnosed with endometrial carcinoma between 1987 and 1991. IHC analysis for ER and PR expression was performed and scored based on staining intensity and the percentage of tumor cells with nuclear staining. Biochemical assays were performed on frozen tissues. Concordance between the two methods was evaluated and hormone receptor status was correlated with tumor grade, stage, recurrence and survival.ER and PR expression, determined by IHC, correlated well with RIA levels (Spearmans correlation coefficient, P = 0.006 and 0.0005, respectively). Determination of ER and PR expression by both methods was correlated with tumor grade. Hazards ratios revealed that the absence of ER and PR expression, determined by both IHC and RIA, independently correlated with recurrence in early stage disease (P < 0.05).Historically, receptors have been determined by RIA. In this study, IHC and RIA were equally suitable for determination of ER and PR. This is significant clinically as IHC has several advantages over RIA, including easier processing, lower cost, greater speed, and applicability to fixed tissue samples. In addition, ER negative status was predictive of the recurrence of Stage I tumors independent of tumor grade. ER status may aid the clinician in planning treatment when adjuvant treatment is controversial." @default.
• W2090172011 created "2016-06-24" @default.
• W2090172011 creator A5002353139 @default.
• W2090172011 creator A5045166306 @default.
• W2090172011 creator A5062209891 @default.
• W2090172011 creator A5063523041 @default.
• W2090172011 date "1999-11-15" @default.
• W2090172011 modified "2023-10-11" @default.
• W2090172011 title "Estrogen receptor status, determined by immunohistochemistry, as a predictor of the recurrence of Stage I endometrial carcinoma" @default.
• W2090172011 cites W1507770182 @default.
• W2090172011 cites W1972450145 @default.
• W2090172011 cites W2003418168 @default.
• W2090172011 cites W2007956592 @default.
• W2090172011 cites W2021212858 @default.
• W2090172011 cites W2024416047 @default.
• W2090172011 cites W2065118454 @default.
• W2090172011 cites W2067682618 @default.
• W2090172011 cites W2068776651 @default.
• W2090172011 cites W2077486811 @default.
• W2090172011 cites W2082692766 @default.
• W2090172011 cites W2092585323 @default.
• W2090172011 cites W2094978614 @default.
• W2090172011 cites W2095301062 @default.
• W2090172011 cites W2135020195 @default.
• W2090172011 cites W2144907668 @default.
• W2090172011 cites W2170234323 @default.
• W2090172011 cites W230934015 @default.
• W2090172011 doi "https://doi.org/10.1002/(sici)1097-0142(19991115)86:10<2083::aid-cncr28>3.0.co;2-2" @default.
• W2090172011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10570435" @default.
• W2090172011 hasPublicationYear "1999" @default.
• W2090172011 type Work @default.
• W2090172011 sameAs 2090172011 @default.
• W2090172011 citedByCount "45" @default.
• W2090172011 countsByYear W20901720112013 @default.
• W2090172011 countsByYear W20901720112014 @default.
• W2090172011 countsByYear W20901720112015 @default.
• W2090172011 countsByYear W20901720112016 @default.
• W2090172011 countsByYear W20901720112018 @default.
• W2090172011 countsByYear W20901720112019 @default.
• W2090172011 countsByYear W20901720112020 @default.
• W2090172011 countsByYear W20901720112021 @default.
• W2090172011 countsByYear W20901720112022 @default.
• W2090172011 crossrefType "journal-article" @default.
• W2090172011 hasAuthorship W2090172011A5002353139 @default.
• W2090172011 hasAuthorship W2090172011A5045166306 @default.
• W2090172011 hasAuthorship W2090172011A5062209891 @default.
• W2090172011 hasAuthorship W2090172011A5063523041 @default.
• W2090172011 hasBestOaLocation W20901720111 @default.
• W2090172011 hasConcept C121608353 @default.
• W2090172011 hasConcept C126322002 @default.
• W2090172011 hasConcept C142724271 @default.
• W2090172011 hasConcept C143998085 @default.
• W2090172011 hasConcept C146357865 @default.
• W2090172011 hasConcept C151730666 @default.
• W2090172011 hasConcept C160798450 @default.
• W2090172011 hasConcept C204232928 @default.
• W2090172011 hasConcept C23589133 @default.
• W2090172011 hasConcept C2777164284 @default.
• W2090172011 hasConcept C2777546739 @default.
• W2090172011 hasConcept C2778311097 @default.
• W2090172011 hasConcept C3018521938 @default.
• W2090172011 hasConcept C530470458 @default.
• W2090172011 hasConcept C71924100 @default.
• W2090172011 hasConcept C84606932 @default.
• W2090172011 hasConcept C86803240 @default.
• W2090172011 hasConcept C98717036 @default.
• W2090172011 hasConceptScore W2090172011C121608353 @default.
• W2090172011 hasConceptScore W2090172011C126322002 @default.
• W2090172011 hasConceptScore W2090172011C142724271 @default.
• W2090172011 hasConceptScore W2090172011C143998085 @default.
• W2090172011 hasConceptScore W2090172011C146357865 @default.
• W2090172011 hasConceptScore W2090172011C151730666 @default.
• W2090172011 hasConceptScore W2090172011C160798450 @default.
• W2090172011 hasConceptScore W2090172011C204232928 @default.
• W2090172011 hasConceptScore W2090172011C23589133 @default.
• W2090172011 hasConceptScore W2090172011C2777164284 @default.
• W2090172011 hasConceptScore W2090172011C2777546739 @default.
• W2090172011 hasConceptScore W2090172011C2778311097 @default.
• W2090172011 hasConceptScore W2090172011C3018521938 @default.
• W2090172011 hasConceptScore W2090172011C530470458 @default.
• W2090172011 hasConceptScore W2090172011C71924100 @default.
• W2090172011 hasConceptScore W2090172011C84606932 @default.
• W2090172011 hasConceptScore W2090172011C86803240 @default.
• W2090172011 hasConceptScore W2090172011C98717036 @default.
• W2090172011 hasIssue "10" @default.
• W2090172011 hasLocation W20901720111 @default.
• W2090172011 hasLocation W20901720112 @default.
• W2090172011 hasOpenAccess W2090172011 @default.
• W2090172011 hasPrimaryLocation W20901720111 @default.
• W2090172011 hasRelatedWork W1601684588 @default.
• W2090172011 hasRelatedWork W1982455337 @default.
• W2090172011 hasRelatedWork W1985436176 @default.
• W2090172011 hasRelatedWork W2104328188 @default.
• W2090172011 hasRelatedWork W2108427450 @default.
• W2090172011 hasRelatedWork W2794513713 @default.
• W2090172011 hasRelatedWork W2806491837 @default.
• W2090172011 hasRelatedWork W2947313698 @default.
• W2090172011 hasRelatedWork W4220795960 @default.

• next