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• W2090199761 abstract "In order to investigate whether the leukemic B cells in B-CLL express immunoglobulin genes in mutated or unmutated form, independent cDNA clones of one patient with B-CLL expressing heavy and light chain V region genes were sequenced. The sequences of both the VH and V kappa clones were identical. The V genes could be assigned to known germline V genes. No somatic mutations were found. At the V kappa-J kappa border there is an insertion of N-sequences which are only rarely found in immunoglobulin light chain genes. Our study confirms other published data on V gene expression in B-CLL in that the surface immunoglobulins in these tumors are unmutated." @default.
• W2090199761 created "2016-06-24" @default.
• W2090199761 creator A5012958604 @default.
• W2090199761 creator A5084142566 @default.
• W2090199761 creator A5091333429 @default.
• W2090199761 date "1991-01-01" @default.
• W2090199761 modified "2023-09-27" @default.
• W2090199761 title "B cells of chronic lymphatic leukemia express V genes in unmutated form" @default.
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• W2090199761 doi "https://doi.org/10.1016/0145-2126(91)90060-7" @default.
• W2090199761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1713635" @default.
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