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• W2090208448 abstract "Microdissected areas of the rabbit brain were isolated at prenatal day E-29, postnatal days P-3, 7, 14, 21, 2 months and adults. Methionine-enkephalin (ME) was assayed by RIA and ME concentration [ME] was expressed relative to the protein content of the extracted brain tissues. In brain nuclei with important roles in respiratory control [ME] was higher in prenatal and early postnatal life than in adults. In contrast, the prenatal and early postnatal [ME] levels in other nuclei were lower than or equal to adult values. These data suggest an important and changing role for ME in respiratory control throughout development. Early high [ME] levels within brainstem respiratory control nuclei may contribute to the newborn's increased susceptibility to respiratory depression." @default.
• W2090208448 created "2016-06-24" @default.
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• W2090208448 date "1985-06-01" @default.
• W2090208448 modified "2023-10-18" @default.
• W2090208448 title "Development of methionine-enkephalin in microdissected areas of the rabbit brain" @default.
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• W2090208448 doi "https://doi.org/10.1016/0006-8993(85)90417-2" @default.
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